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Clinical and evolutive aspects in IgE-mediated food allergy in infants and small children
The skin, respiratory and gastrointestinal allergy manifestations can evolves alternatively or concomitant in the first years of life; food sensitization is the common etiology. The objective of this study is the assessment of IgE-mediated food allergy regarding clinical manifestations and their correlation with risk factors, the dietary and drug therapy impact during a 22 months monitoring. Results. The onset food allergy manifestations (mean age 5-11 months) involve skin (66 cases), respiratory (55 cases) and/or gastrointestinal tract (5 cases). We evidenced respiratory aeroallergens sensitization (bronchial asthma and/or allergic rhinitis) in 50 percents of cases. 43 children achieved oral tolerance for one or more foodS, most commonly in milk and egg white allergy. Conclusions. The secondary and tertiary food allergy prevention measures are not allways be able to prevent the progression of atopic march to polisensitizations and complex clinical manifestations.
Key words: evolution, small child, food allergy