Angelica Cristina Marin

Latest posts by Angelica Cristina Marin (see all)

DIAGNOSTIC SI TRATAMENT IN BOALA DE REFLUX GASTROESOFAGIAN – POSIBILITATI SI LIMITE - 03/11/2016
DIAGNOSIS AND TREATMENT IN GASTROESOPHAGEAL REFLUX DISEASE – POSSIBILITIES AND LIMITATIONS - 03/11/2016
ULCERUL GASTRIC DUPA ADMINISTRAREA PE TERMEN SCURT DE ANTIINFLAMATOARE NESTEROIDIENE LA UN COPIL MIC – PREZENTARE DE CAZ - 28/01/2016

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

DIAGNOSTIC SI TRATAMENT IN BOALA DE REFLUX GASTROESOFAGIAN – POSIBILITATI SI LIMITE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 3, An 2016

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

Angelica Cristina Marin, Claudia Olaru, Gabriela Ciubotariu, Marin Burlea, Mihaela Moscalu, Nicoleta Gimiga and Smaranda Diaconescu

REZUMAT

Departajarea refluxului gastro-esofagian (RGE) fiziologic (cel mai frecvent) de boala de reflux gastro-esofagian (BRGE) în primul an de viaţă este obligatorie pentru a evita farmacoterapia agresivă. La toate vârstele
copilăriei se aplică criterii moderne de evaluare clinică, sumând simptome digestive şi/sau extradigestive şi rezultatele unor investigaţii moderne. Tratamentul igieno-dietetic (suficient in RGE fiziologic), obligatoriu în toate cazurile, şi inhibitorii de pompă protonică dupa vârsta de un an induc remisiune în majoritatea cazurilor de RGE. Evoluţia cronică/recidivantă şi rezistenţa la tratamentul comun impun intervenţia chirurgicală, domeniu îmbogaţit recent la copil cu miotomia perorală endoscopică (POEM).

Cuvinte cheie: boală de reflux gastroesofagian, inhibitori de pompă de protoni, miotomia perorală endoscopică

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Angelica Cristina Marin

DIAGNOSIS AND TREATMENT IN GASTROESOPHAGEAL REFLUX DISEASE – POSSIBILITIES AND LIMITATIONS

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Angelica Cristina Marin, Claudia Olaru, Gabriela Ciubotariu, Marin Burlea, Mihaela Moscalu, Nicoleta Gimiga and Smaranda Diaconescu

ABSTRACT

In children’s first year of life it is mandatory to make a difference between physiological gastroesophageal reflux (GER) and gastroesophageal reflux disease (GERD), in order to avoid an aggressive pharmacologic therapy. All ages of childhood benefit from modern criteria of clinical evaluation, by corroborating the digestive or extradigestive symptoms with the results of modern investigations. The dietary measures (sufficient in GER but mandatory in all cases) together with proton pump inhibitors administration after one year of age induce remission in majority of GER cases. The chronic and recurrent evolution of the disease or failure of the common treatment require surgical intervention, recently enriched in children with peroral endoscopic myotomy (POEM).

Keywords: gastroesophageal reflux disease, proton pump inhibitors, Peroral Endoscopic Myotomy

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Angelica Cristina Marin

ULCERUL GASTRIC DUPA ADMINISTRAREA PE TERMEN SCURT DE ANTIINFLAMATOARE NESTEROIDIENE LA UN COPIL MIC – PREZENTARE DE CAZ

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Ancuta Ignat, Gabriela Paduraru, Angelica Cristina Marin, Anamaria Ciubara, Valeriu V. Lupu and Marin Burlea

REZUMAT

Agenţii antiinflamatori nesteroidieni (AINS) produc leziuni gastrice prin intermediul a două mecanisme: iritaţia locală şi acţiunea sistemică. Un copil în vârstă de 2 ani şi 10 luni, sex feminin, a primit AINS timp de 2 zile pentru o infecţie acută a tractului respirator superior şi a prezentat vărsături în „zaţ de cafea“ o zi mai târziu. Endoscopia digestivă superioară a evidenţiat o leziune de ulcer gastric. Biopsia gastrică a fost negativă pentru infecţia cu H. pylori, iar pacienta a fost diagnosticată cu ulcer gastric acut indus de consumul de AINS în absenţa altor cauze de ulcer gastric. Ulcerele gastrice se dezvoltă foarte rar după o administrare pe termen scurt de AINS, fapt ce a determinat raportarea acestui caz. Luând în considerare atât riscurile cât şi beneficiile terapiei cu AINS, este indicat ca în cazul fiecărui pacient care trebuie să urmeze un tratament cronic cu medicamente antiinflamatorii să fie căutaţi posibilii factori de risc asociaţi.

Cuvinte cheie: medicamente antiinflamatoare nesteroidiene (AINS), ulcer gastric, copil

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Ancuta Ignat

GASTRIC ULCER AFTER SHORT-TERM NONSTEROIDAL ANTI-INFLAMMATORY DRUGS ADMINISTRATION IN A SMALL CHILD – CASE REPORT

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Ancuta Ignat, Gabriela Paduraru, Angelica Cristina Marin, Anamaria Ciubara, Valeriu V. Lupu and Marin Burlea

ABSTRACT

Nonsteroidal anti-inflammatory agents (NSAIDs) produce gastric lesions through two mechanisms: local irritation and systemic action. A 2 year and 10 months old female received NSAID for acute upper respiratory infection for 2 days and she developed coffee ground vomitus one day later. Upper gastrointestinal endoscopy revealed a gastric ulcer. She was negative for H. pylori infection, and she was diagnosed with NSAID – induced acute gastric ulcer in the absence of other causes of gastric ulcer. Gastric ulcers develop very rarely after a short-term administration of NSAIDs, which prompted us to report this case. Balancing the risk and the benefit of eradication therapy, it is indicated, for every patient who must follow a chronic treatment with anti-inflammatory drugs, to look for possible associated risk factors.

Keywords: anti-inflammatory drugs (NSAIDs), gastric ulcer, child

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Ancuta Ignat

GASTRITELE SI HELICOBACTER PYLORI LA COPIL – DIAGNOSTICUL ENDOSCOPIC PRIMAR SI SECUNDAR

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 3, An 2015

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Valeriu V. Lupu, Gabriela Paduraru, Ancuta Ignat, Eliza Tighici-Saizu, Claudia Olaru, Nicoleta Gimiga, Angelica Cristina Marin, Cornelia Savescu, Ioana Florea and Marin Burlea

REZUMAT

Infecţia cu Helicobacter pylori (H. pylori) este o problemă comună şi semnificativă de sănătate publică.
Obiectiv. Determinarea prevalenţei infecţiei cu H. pylori la copiii cu simptomatologie sugestivă şi conturarea cazurilor în funcţie de tipul şi felul gastritei prin efectuarea de endoscopii digestive superioare.
Material şi metodă. Studiu retrospectiv realizat pe o perioadă de 5 ani pe 1.269 de copii cu simptomatologie gastrică, la care s-au efectuat endoscopii cu biopsie, stabilindu-se rata de infecţie cu H. pylori prin examen direct sau testul ureazei.
Rezultate. Frecvenţa H. pylori în cazul gastritei acute a fost semnificativ mai mică (34,78%) comparativ cu frecvenţa acesteia în cazul gastritei cronice (54,94%). În cadrul celor 10 tipuri de gastrită, cele mai frecvente sunt formele purpurice (43,66%), nodular purpurică (25,93%) şi nodular antrală (15,84%), la polul opus situându-se gastrita atrofică şi hipertrofică. Asocierile cele mai frecvente decelate endoscopic sunt cu esofagita gr I în 51,6%, duodenita în 45,07% şi forma purpurică în 24,74%.
Concluzii. Infecţia cu H. pylori este cel mai frecvent asociată gastritei cronice (54,94%). Identificarea precoce a infecţiei este esenţială pentru eradicarea bacteriei şi prevenirea apariţiei diferitelor tipuri de gastrită identificate endoscopic.

Cuvinte cheie: gastrită, H. pylori, endoscopie, copil

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Valeriu V. Lupu

GASTRITIS AND HELICOBACTER PYLORI IN CHILDREN – PRIMARY AND SECONDARY ENDOSCOPIC DIAGNOSIS

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Valeriu V. Lupu, Gabriela Paduraru, Ancuta Ignat, Eliza Tighici-Saizu, Claudia Olaru, Nicoleta Gimiga, Angelica Cristina Marin, Cornelia Savescu, Ioana Florea and Marin Burlea

ABSTRACT

The infection with Helicobacter pylori (H pylori) represents an important issue of public health.
Aim. Establishing the prevalence of H. pylori infection in children and presenting the cases according to the gastritis type by performing upper digestive endoscopies.
Material and method. The retrospective study referred to a period of 5 years and included 1269 children evaluated by upper endoscopy to establish the H. pylori infection rate.
Results. The frequency of H. pylori in the case of acute gastritis was significantly more reduced (34.78%) than in the case of chronic gastritis (54.94%). Referring to the 10 types of gastritis, the most frequent ones are purpuric (43.66%), nodular purpuric (25.93%) and nodular antral (15.84%). At the other end, atrophic and hypertrophic gastritis were positioned. The most frequent associations pointed out endoscopically are those with 1st degree esophagitis - 51.6%, duodenitis – 45.07% and purpuric duodenitis – 24.74%.
Conclusions. The H. pylori infection is the most frequent etiologic factor for chronic gastritis (54.94%). The early identification of the infection is essential to destroy the bacteria and to prevent the development of various types of gastritis that are later on endoscopically identified.

Keywords: gastritis, H. pylori, upper endoscopy, child

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Valeriu V. Lupu

ASPECTE ETICE PRIVIND RECOLTAREA SANGELUI DIN CORDONUL OMBILICAL IN SCOP DIAGNOSTIC

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Elena Tataranu, Maria Stamatin, Smaranda Diaconescu, Angelica Cristina Marin, Cornelia Savescu and Marin Burlea

REZUMAT

Aprofundarea studiilor privind mecanismele genetice şi epigenetice (determinate de mediu) ale atopiei a adus dezvăluiri privind debutul intrauterin al alergiei, dovedit de prezenţa IgE în sângele cordonului ombilical. Depistarea acestor nou-născuţi şi includerea lor într-un program de îngrijiri specifice reduc morbiditatea ulterioară din cadrul marşului alergic cu efecte incontestabile asupra calităţii vieţii şi a costurilor de îngrijire medicală. Creşterea dramatică a prevalenţei atopiei în ultimele decenii sugerează importanţa determinărilor IgE în cordonul ombilical. Utilizarea în scop diagnostic a sângelui cordonului ombilical impune însă legi şi reguli clare care fac obiectul dezbaterii din prezenta lucrare.

Cuvine cheie: consimţământ informat, sânge din cordon ombilical, atopie, IgE

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Elena Tataranu

ETHICAL ASPECTS ABOUT INFORMED CONSENT IN CORD BLOOD COLLECTION FOR DIAGNOSTIC PURPOSES

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Elena Tataranu, Maria Stamatin, Smaranda Diaconescu, Angelica Cristina Marin, Cornelia Savescu and Marin Burlea

ABSTRACT

Deepening the knowledge about genetic and epigenetic mechanisms studies (environmental caused) regarding atopy, brought revelations about intrauterine onset of allergies, proven by the presence of IgE in umbilical cord blood. Detection of these newborns and their inclusion in a specific care program further reduces the morbidity of allergic march with the undeniable effects on quality of life and healthcare costs. The dramatic increase in the prevalence of atopy in recent decades suggests the importance of IgE in umbilical cord determinations. The use of umbilical cord blood for diagnostic purposes requires clear laws and rules and this is the subject we suggest to debate in this paper.

Keywords: informed consent, cord blood, atopy, IgE

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Elena Tataranu

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