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Elena Tataranu

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Articole semnate de acelasi autor in Revista Romana de Pediatrie:

ASPECTE ETICE PRIVIND RECOLTAREA SANGELUI DIN CORDONUL OMBILICAL IN SCOP DIAGNOSTIC

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Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 3, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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National Awards “Science and Research”

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Promoting Global Health

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ASPECTE ETICE PRIVIND RECOLTAREA SANGELUI DIN CORDONUL OMBILICAL IN SCOP DIAGNOSTIC

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REZUMAT

Aprofundarea studiilor privind mecanismele genetice şi epigenetice (determinate de mediu) ale atopiei a adus dezvăluiri privind debutul intrauterin al alergiei, dovedit de prezenţa IgE în sângele cordonului ombilical. Depistarea acestor nou-născuţi şi includerea lor într-un program de îngrijiri specifice reduc morbiditatea ulterioară din cadrul marşului alergic cu efecte incontestabile asupra calităţii vieţii şi a costurilor de îngrijire medicală. Creşterea dramatică a prevalenţei atopiei în ultimele decenii sugerează importanţa determinărilor IgE în cordonul ombilical. Utilizarea în scop diagnostic a sângelui cordonului ombilical impune însă legi şi reguli clare care fac obiectul dezbaterii din prezenta lucrare.

Cuvine cheie: consimţământ informat, sânge din cordon ombilical, atopie, IgE

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ETHICAL ASPECTS ABOUT INFORMED CONSENT IN CORD BLOOD COLLECTION FOR DIAGNOSTIC PURPOSES

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Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 3, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

ETHICAL ASPECTS ABOUT INFORMED CONSENT IN CORD BLOOD COLLECTION FOR DIAGNOSTIC PURPOSES

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ABSTRACT

Deepening the knowledge about genetic and epigenetic mechanisms studies (environmental caused) regarding atopy, brought revelations about intrauterine onset of allergies, proven by the presence of IgE in umbilical cord blood. Detection of these newborns and their inclusion in a specific care program further reduces the morbidity of allergic march with the undeniable effects on quality of life and healthcare costs. The dramatic increase in the prevalence of atopy in recent decades suggests the importance of IgE in umbilical cord determinations. The use of umbilical cord blood for diagnostic purposes requires clear laws and rules and this is the subject we suggest to debate in this paper.

Keywords: informed consent, cord blood, atopy, IgE

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Chronical constipation multifactorial etiopathogeny in childhood

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 2, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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DOI - Crossref
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DOAJ
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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

Chronical constipation multifactorial etiopathogeny in childhood

, , , , and

ABSTRACT

Constipation is an apparently common condition in children, but it has important consequences in pediatric age. Its prevalence varies between 0.7 and 29.6% (with an average of 8%), with no important difference between sexes. The etiology still remains unclear, and although many mechanisms involved in this disease were discovered, it is still very heterogenous. Constipation may be functional, related with an inadequate diet or with psychical circumstances which influences the normal act of defecation, organic, in which gastrointestinal diseases and not only, play a big role, or it may be talked about a genetic determinism. Specific associated gene mutations haven’t been related yet. There are plenty of genetic syndromes in which constipation is a frequent symptom. Trying to objectify the diagnosis, many types of classifications were suggested, based on the main types of the symptoms. Despite of this, diagnosing constipation in children still remains an important challenge.

Key words: child, constipation, delayed bowel movements

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ETIOPATOGENIA MULTIFACTORIALA A CONSTIPATIEI CRONICE LA VARSTA PEDIATRICA

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 2, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
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DOAJ
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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

ETIOPATOGENIA MULTIFACTORIALA A CONSTIPATIEI CRONICE LA VARSTA PEDIATRICA

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REZUMAT

Constipaţia este o patologie aparent banală, dar cu implicaţii importante la vârsta pediatrică. Prevalenţa acesteia variază de la 0,7% la 29,6% (în medie 8%), fără o diferenţă semnificativă între sexe. Etiologia constipaţiei rămâne încă neclară, fiind extrem de heterogenă în ciuda identificării a numeroase mecanisme ce stau la baza acestei afecţiuni. Constipaţia poate fi de natură funcţională, corelată cu o dietă neadecvată sau cu circumstante de natură psihică ce influenţează desfăşurarea normală a defecaţiei, organică, având la bază diferite boli ale tractului gastrointestinal şi nu numai, sau poate avea determinism genetic. Cu toate acestea, încă nu s-au găsit mutaţii genice asociate în mod specific. Numeroase sindroame genetice asociază ca mainifestare clinică constipaţia. În încercarea concretizării diagnosticului au fost propuse diferite clasificări bazate pe simptomatologie. Cu toate acestea, diagnosticul constipaţiei la populaţia pediatrică poate fi dificil de stabilit.

Cuvinte cheie: copil, constipaţie, tranzit intestinal încetinit

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Diagnosis and management in chronic constipation in children age (Part II)

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 3, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
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Ebsco Host - Medline
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

Diagnosis and management in chronic constipation in children age (Part II)

, , , , and

ABSTRACT

Constipation is a common health problem that affects children of all ages. The etiology is often functional, being the result of voluntary retention of the stool. A complete case history and a detailed physical examination are essential for an appropriate diagnosis. In most cases laboratory investigations are not required; they are indicated when a suspicion of an organic cause occurs (Hirschsprung disease, pseudoobstruction, hypothyroidism, diabetes insipidus, cystic fibrosis, congenital anorectal malformations) or in treatment-resistant cases. Early diagnosis is extremely important being associated with a better response to therapy. This includes performing DRE, colonoscopy, scintigraphy, colon videocapsule and anorectal manometry. The first stage of functional constipation treatment consists in desimpactation. Polyethylene glycol is effective and well tolerated. After desimpactation, a long-term maintenance program is necessary, due to increased frequency of relapses. Maintenance drugs include mineral oil, lactulose, polyethylene glycol and sorbitol. A diet rich in dietary fiber associated with family support and, when possible, child education are essential. The delay in diagnosis and treatment can lead to the progression into a chronic health problem with physical, psychological and social implications.

Key words: constipation, colonoscopy, anorectal manometry, child

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DIAGNOSTIC SI MANAGEMENT IN CONSTIPATIA CRONICA LA COPIL (Partea a II-a)

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 3, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

DIAGNOSTIC SI MANAGEMENT IN CONSTIPATIA CRONICA LA COPIL (Partea a II-a)

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REZUMAT

Constipaţia este o problemă comună care afectează copiii de toate vârstele. De cele mai multe ori etiologia este de natură funcţională, fiind rezultatul retenţiei voluntare a scaunului. Un rol important în stabilirea diagnosticului îl au obţinerea unei anamneze complete şi efectuarea unui examen fizic detaliat. În majoritatea cazurilor investigaţiile paraclinice nu sunt necesare pentru diagnostic, ele fiind indicate atunci când există suspiciunea unei cauze organice de constipaţie (boala Hirschsprung, pseudoobstrucţie, hipotiroidism, diabet insipid, fibroză chistică, malformaţii anorectale congenitale) sau în cazurile cu rezistenţă la tratament. Diagnosticul precoce este extrem de important, fiind asociat cu un răspuns mai bun la terapie. Acesta include efectuarea tuşeului rectal, colonoscopia, scintigrafia colonică, videocapsulă şi manometria anorectală. Prima etapă a tratamentului constipaţiei funcţionale constă în dezimpactare. Polietilen glicolul este eficace şi bine tolerat. După dezimpactare este iniţiat un program de întreţinere pe termen lung, din cauza frecvenţei crescute a recidivelor, cu medicamente ca uleiul mineral, lactuloza, polietilenglicolul şi sorbitolul. Regimul alimentar bogat în fibre alimentare asociat cu educaţia familiei şi, atunci când este posibil, a copilului este esenţial. Întârzierea diagnosticului şi implicit a tratamentului poate duce la progresia spre o problemă cronică semnificativă de sănătate cu implicaţii fizice, psihologice şi sociale.

Cuvinte cheie: constipaţie, colonoscopie, manometrie anorectală, copil

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