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Lavinia Chiţimuş

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Articole semnate de acelasi autor in Revista Romana de Pediatrie:

Neurological manifestations in children with autism

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 2, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Neurological manifestations in children with autism

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ABSTRACT

The autism is a pervasive developmental disorder that can be associated with various neurological disorders. The aim of this study is to evaluate the incidence and characteristics of neurological abnormalities, the presence of epileptic seizures and/or EEG abnormalities in children with autism. Our study included 34 children (aged 2.5 to 13 years) diagnosed with autism. The study protocol included: general physical and neurological examination, IQ, tests of language, behavior, auditory attention, social skills and play, clinical features of epileptic seizures, EEG recordings. Neurological exam revealed mild hypotonia in 19 (55.88%) patients with autism, hyporeflexia in 21 (61.76%), the presence of stereotype movements in 24 (70.58%) and abnormalities of gait in 5 (14,80%) cases. Epileptic seizures were present in 9 children. EEG changes were present in all children diagnosed with autism and epilepsy, but also in those with no clinically critical episodes; they were represented by nonepileptic type in 29.41% cases and epileptic abnormalities in 44.12%. The changes of tone and reflexes, seizures and epileptic discharges were particularly common in children studied with autism. Our data suggests that EEG evaluation is important for these patients. The management of epilepsy in autism consists in the administration of antiepileptic drugs that, in addition to seizures control, also interfere with mood and behavioral disturbance observed in autism.

Key words: autism, child, epilepsy, EEG abnormalities, neurological abnormalities

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MANIFESTARI NEUROLOGICE LA COPIII CU AUTISM

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 2, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

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DOAJ
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ICMJE- Recommendations

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MANIFESTARI NEUROLOGICE LA COPIII CU AUTISM

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REZUMAT

Autismul este o afecţiune pervazivă de dezvoltare care se poate asocia cu diferite probleme neurologice. Scopul acestui studiu a fost de a evalua incidenţa şi caracteristicile anomaliilor evidenţiate la examenul neurologic, prezenţa crizelor epileptice şi/sau anomaliile EEG la copiii cu autism. În studiu au fost incluşi 34 de copii cu vârste cuprinse între 2 ani şi 5 luni-13 ani, diagnosticaţi cu autism. Protocolul de studiu a inclus: examenul clinic general şi neurologic, QI, evaluarea limbajului, comportamentului, atenţiei, abilităţilor sociale şi a jocului, caracteristicile clinice ale crizelor epileptice, înregistrarea EEG. Examenul neurologic a evidenţiat hipotonie musculară la 19 (55,88%) pacienţi, diminuarea reflexelor osteotendinoase la 21 (61,76%), prezenţa mişcărilor stereotipe la 24 (70,58%) şi anomalii ale mersului la 5 (14,70%) dintre copiii cu autism evaluaţi. Crize epileptice au prezentat 9 copii. Modificările EEG au fost prezente la toţi copiii diagnosticaţi cu autism şi epilepsie, dar şi la cei care nu prezentau clinic episoade critice, fiind reprezentate de anomalii neepileptice în 29,41% din cazuri şi de tip epileptic în 44,12%. Modificările de tonus muscular şi de reflexe, crizele şi descărcările epileptice au fost comune la copiii cu autism. Rezultatele studiului actual demonstrează că evaluarea EEG este importantă la aceşti pacienţi. Abordarea terapeutică a epilepsiei în autism a constat în administrarea de medicamente antiepileptice care, pe lângă controlul crizelor, au influenţat favorabil atât dispoziţia, cât şi comportamentul.

Cuvinte cheie: autism, copil, epilepsie, modificări EEG, anomalii neurologice

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Upper digestive tract manifestations inCRF patients on dialysis

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Revista Romana de PEDIATRIE | Volumul LXI, Nr. 2, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Upper digestive tract manifestations inCRF patients on dialysis

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REZUMAT

Background: CRF patients are prone to a wide range of complications: gastroesophageal reflux disease, esophagitis, gastropathy, gastritis and duodenitis, gastric and duodenal ulcer, angiodysplasia.

Objectives: the study’s aim was to highlight the gastro-duodenal symptoms, the frequency of pathological modifi cations of eso-gastro-duodenal mucous membrane and the presence of H.pylori in CRF children receiving dialysis.

Material and methods: the study included 55 children admitted to the IVth Pediatric Nephrology Clinic of the Emergency Clinical Hospital “Sf Maria” Iasi, all receiving dialysis, to which was applied a systematized protocol: objective and subjective symptoms and the results of upper gastrointestinal endoscopy. The study included patients with mucosal changes detected endoscopically.

Conclusions: Pathological modifications of the upper digestive tract mucous membrane in children on chronic dialysis are inconstant, suggesting the need for endoscopy in each case. H.pylori was found in 24/55 (43.63%) biopsies and points out the relatively frequent association between gastro-duodenal lesions and H.pylori in chronic dialysis patient.

Key words: esophagitis, gastritis, H.pylori, dialysis

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MANIFESTARILE TUBULUI DIGESTIV SUPERIOR LA PACIENTUL CU IRC DIALIZAT

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Revista Romana de PEDIATRIE | Volumul LXI, Nr. 2, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Ebsco Host - Medline
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Semantic Scholar

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ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

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MANIFESTARILE TUBULUI DIGESTIV SUPERIOR LA PACIENTUL CU IRC DIALIZAT

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REZUMAT

Introducere: bolnavii cu IRC sunt susceptibili la o gamă largă de complicaţii: reflux gastro-esofagian, esofagită, gastropatie, gastrită şi duodenită, ulcer gastric şi duodenal, angiodisplazie. Obiective: studiul a constat în evidenţierea simptomelor gastro-duodenale, a frecvenţei modificărilor patologice ale mucoasei eso-gastro-duodenale şi a prezenţei H.pylori la copiii cu IRC aflaţi în program de dializă. Material şi metodă: lotul de studiu a fost format din 55 de copii internaţi în Clinica a IV-a Nefrologie, aflaţi în program de substituţie renală cronică, la care s-a aplicat un protocol ce a sistematizat: simptomele obiective şi subiective şi rezultatele endoscopiei digestive superioare. Lotul cuprinde bolnavii cu modificări ale mucoasei depistate endoscopic. Concluzii: modificările patologice ale mucoasei eso-gastro-duodenale la copilul dializat cronic se reflectă clinic inconstant, ceea ce sugerează necesitatea endoscopiei pentru fiecare caz. Prezenţa H.pylori la 24/55 (43,63%) cazuri biopsiate evidenţiază asocierea relativ frecventă între leziunile gastro-duodenale şi H.pylori la pacienţii dializaţi cronic.

Cuvinte cheie: esofagită, gastrită, H.pylori, dializǎ

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