National Awards “Science and Research”
NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.
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Upper digestive tract manifestations inCRF patients on dialysis
L. Perţea, Lavinia Chiţimuş, Smaranda Diaconescu, Valeriu V. Lupu, Maria Florea, M. Burlea and O. Brumariu
Background: CRF patients are prone to a wide range of complications: gastroesophageal reflux disease, esophagitis, gastropathy, gastritis and duodenitis, gastric and duodenal ulcer, angiodysplasia.
Objectives: the study’s aim was to highlight the gastro-duodenal symptoms, the frequency of pathological modifi cations of eso-gastro-duodenal mucous membrane and the presence of H.pylori in CRF children receiving dialysis.
Material and methods: the study included 55 children admitted to the IVth Pediatric Nephrology Clinic of the Emergency Clinical Hospital “Sf Maria” Iasi, all receiving dialysis, to which was applied a systematized protocol: objective and subjective symptoms and the results of upper gastrointestinal endoscopy. The study included patients with mucosal changes detected endoscopically.
Conclusions: Pathological modifications of the upper digestive tract mucous membrane in children on chronic dialysis are inconstant, suggesting the need for endoscopy in each case. H.pylori was found in 24/55 (43.63%) biopsies and points out the relatively frequent association between gastro-duodenal lesions and H.pylori in chronic dialysis patient.
Key words: esophagitis, gastritis, H.pylori, dialysis