Corina Paul

Latest posts by Corina Paul (see all)

DIFICULTATI DE DIAGNOSTIC IN HIPOGLICEMIA SUGARULUI - 20/11/2015
DIAGNOSIS DIFFICULTIES IN INFANT’S HYPOGLYCEMIA - 20/11/2015
Height deficit associated to prolactinoma – case report - 03/08/2015

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

DIFICULTATI DE DIAGNOSTIC IN HIPOGLICEMIA SUGARULUI

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 3, An 2015

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

Alina Grama, Oana Marginean, Iulian Velea, Corina Paul, Mihaela Chincesan and Lorena Elena Melit

REZUMAT

Introducere. Hipoglicemia cu diversele ei cauze este frecvent semnalată în patologia pediatrică, începând din perioada neonatală şi până în adolescenţă. Prin consecinţele ei atât cele imediate (convulsii, comă), cât şi cele tardive (afectare neurologică), hipoglicemia trebuie cunoscută, prevenită, evitată şi tratată.
Obiective. Prezentarea evoluţiei clinice a unei paciente cu hipoglicemie severă simptomatică încă din perioada de nou-născut. De la naştere, valoarea glicemiei prezintă o dinamică fluctuantă, iar scăderea glicemiei, izolat, nu reprezintă neapărat o situaţie patologică, dar poate fi un simptom al unei patologii subiacente.
Material şi metodă. Pacienta este internată în clinica noastră la vârsta de nou-născut, în vederea stabilirii etiologiei şi tratamentului hipoglicemiilor. Am realizat profilul biologic şi hormonal, am efectuat determinări sanguine metabolice şi teste genetice.
Rezultate. Am stabilit diagnosticul de hipoglicemie severă persistentă. Interpretarea rezultatelor a fost îngreunată de evoluţia trenantă a bolii, vârsta mică şi complianţa scăzută din partea familiei.
Concluzii. Hipoglicemia persistentă are cauze multiple. Managementul unui sugar cu hipoglicemie severă poate fi dificil şi impune o abordare complexă.

Cuvinte cheie: hipoglicemie, sugar, gena Duarte

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Alina Grama

DIAGNOSIS DIFFICULTIES IN INFANT’S HYPOGLYCEMIA

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Alina Grama, Oana Marginean, Iulian Velea, Corina Paul, Mihaela Chincesan and Lorena Elena Melit

ABSTRACT

Introduction. Hypoglycemia with its diverse causes is frequently encountered in the pediatrics pathology, beginning with the neonatal period and until the adolescent one. Through its consequences, both, the early (seizures, coma) and the late ones (neurological impairment), hypoglycemia must be identified, prevented, avoided and treated.
Objectives. To present the clinical evolution of a female patient with severe, symptomatic hypoglycemia even since the neonatal period. Since birth, the value of glycaemia presents a fluctuant dynamic, and the isolated decrease of glycaemia does not necessary represent a pathological situation, but can be a symptom of an underlying disorder.
Material and method. The patient is admitted in our clinic at the age of newborn in order to establish the etiology and treatment of hypoglycemia. We achieved the biologic and hormonal profile, we performed metabolic blood determinations and genetic tests. Results. We established the diagnosis of severe persistent hypoglycemia. The burden of the results interpretation was represented by the prolonged evolution of the disease, the small age and the family’s low compliance.
Conclusions. Persistent hypoglycemia has multiple causes. The management of an infant with severe hypoglycemia can be difficult and it imposes a complex approach.

Keywords: hypoglycemia, infant, Duarte gene

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Alina Grama

Height deficit associated to prolactinoma – case report

Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

I. Velea, Corina Paul, Ionela Tămăşan, F. Bîrsăşteanu, Mirela Mogoi and Loredana Todorescu-Negru

ABSTRACT

The pituitary lies within the sella turcica and has a very important role in the regulation of the neuro-endocrine functions through its hormones. Prolactinoma represents a benign tumor of the pituitary (adenoma) which excesively produces the hormon called prolactin. The authors present the case of a male adolescent 16 years old, evaluated in the pediatrics ambulatory for height deficit. On this ocassion increased levels of prolactin were revealed. Later on the patient was admitted in Clinic II Pediatrics to complete investigation for diagnosis.

Key words: height defi cit, prolactin, growth hormone

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I. Velea

KALLMANN Syndrome – case report

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

I. Velea, Corina Paul, Ionela Tămăşan, Loredana Todorescu-Negru, E. Boia, F. Bîrsăşteanu and D. Oneţ

ABSTRACT

Kallmann Syndrome is classically characterized by isolated GnRH deficit associated with hypo/anosmia. Clinically the patients presented micropenis, cryptorchidism, absence of puberty occurence, infertility. The paper presents the case of an adolescent aged 16, presenting anosmia and hypogonadism (observed by family) even since he was 3 years old. He was evaluated repeatedly in different medical services, but no clear diagnosis was made. Finally, the patient was admitted in Clinic II Pediatrics for investigations and diagnosis.

Key words: anosmia, hypogonadism, testosteron

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I. Velea

DEFICIT STATURAL ASOCIAT PROLACTINOMULUI

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

I. Velea, Corina Paul, Ionela Tămăşan, F. Bîrsăşteanu, Mirela Mogoi and Loredana Todorescu-Negru

REZUMAT

Glanda hipofiză este situată la baza creierului, într-o formaţiune anatomică osoasă numită şaua turcească (sella turcica). Are un rol extrem de important în reglarea funcţiilor neuro-endocrine datorită hormonilor secretaţi. Prolactinomul reprezintă o tumoră benignă a glandei hipofize (adenom), ce produce în exces un hormon numit prolactina. Autorii prezintă cazul unui adolescent în vârstă de 16 ani, evaluat în ambulator pentru deficit staturo-ponderal, ocazie cu care s-au decelat valori crescute ale prolactinei serice. Ulterior, pacientul se internează în Clinica II Pediatrie pentru investigaţii suplimentare şi precizare de diagnostic.

Cuvinte cheie: deficit statural, prolactină, hormon de creştere

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I. Velea

SINDROM KALLMANN

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

I. Velea, Corina Paul, Ionela Tămăşan, Loredana Todorescu-Negru, E. Boia, F. Bîrsăşteanu and D. Oneţ

REZUMAT

Sindromul Kallmann se caracterizează prin deficit izolat de GnRH, asociat cu hipo/anosmie. La examenul clinic al pacienţilor cu sindrom Kallmann se decelează micropenis, criptorhidie, absenţa instalării pubertăţii, infertilitate. Se prezintă cazul unui adolescent în vârstă de 16 ani, afirmativ cu anosmie şi hipogonadism (sesizat de aparţinători) încă de la vârsta de 2-3 ani. A fost evaluat în repetate rânduri în diferite servicii medicale, fără a se stabili un diagnostic de certitudine. Ulterior, pacientul se internează în Clinica II Pediatrie pentru investigaţii suplimentare şi precizare de diagnostic.

Cuvinte cheie: anosmie, hipogonadism, testosteron

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I. Velea

Metabolic syndrome in an adolescent – case report

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Corina Paul, I. Velea and Ionela Tămăşan

ABSTRACT

The metabolic syndrome (MS) represents a sum of risk factors leading to the occurence of cardio-vascular diseases and diabetes mellitus (DM). Of these factors we can mention: abdominal obesity, dyslipidemia, arterial hypertension, impaired glucose tolerance. That is why the early depistation of the children at risk to develop MS becomes extremely important. At the end of XXth century, the incidence of type 2 DM dramatically increased. This tendency to increase of type 2 DM prevalence in children is caused by an increase of obesity rate within the young individuals. Although the phyisio-pathological mechanisms of the MS are not clear yet, it seems that the insulin resistance has a key role. Actually, IR represents a disturbed response to the physiologic effects of insulin (affecting the metabolism of the carbohydrates, lipids and protein and also the function of the vascular endothelium). The paper presents the case of an adolescent girl, aged 13, with history of LGA (large for gestational age; birth weight = 5.040 g), with weight excess since she was a small child. The patient was addressed to Clinic II Pediatrics when beside weight excess she also associated high blood pressure.

Key words: metabolic syndrome, child, insulin resistance

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Corina Paul

SINDROMUL METABOLIC LA COPIL

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Corina Paul, I. Velea and Ionela Tămăşan

REZUMAT

Sindromul incisivului maxilar median unic este o afecţiune complexă, datorată unor defecte multiple de dezvoltare, în special pe linia mediană, secundar acţiunii unor factori necunoscuţi, care acţionează în zilele 35-38 de viaţă intrauterină. Autorii prezintă cazul copilului V.C. în vârstă de 13 ani 9 luni, cu repetate internări în vederea evaluării pentru hipostatură şi retard mental. La vârsta de 5 ani a fost diagnosticat cu astm bronşic, iar la vârsta de 10 ani cu panhipopituitarism; a urmat tratament de substituţie tiroidiană şi cu hormon de creştere, dar inconstant. Examenul clinic: retard statural marcat, facies dismorf, obstrucţie nazală cronică, prezenţa incisivului maxilar median unic, retard mental moderat, cu deficit de atenţie. Examinări paraclinice: CT cranian – hipoplazie hipofizară, determinările hormonale au confirmat diagnosticul de panhipopituitarism.

Cuvinte cheie: sindromul incisivului maxilar median unic, copil

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Corina Paul

Pineal gland tumor

Revista Romana de PEDIATRIE | Volumul LX, Nr. 4, An 2011

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Corina Paul, Iulian Velea, Ionela Tămăşan, Carmen Postelnicu, Florin Bîrsăşteanu, Luiza Bădescu and Otilia Angi Cinca

ABSTRACT

The pineal gland tumors represent 3-8% from the total number of cerebral tumors in the child. The mean age at onset ranges between 10 and 13 years. Symptoms are correlated tightly with both the anatomic relations of the pineal gland and the hystological structure of the tumor. The most encountered simptoms include headache, nausea, vomiting, all having as cause the compression on the surrounding tissues and the consecutive hydrocephaly. The authors present a 6 years old female child admitted in Clinic II Pediatrics for repeated vomiting, headache. Eye background examination revealed the papila of the optic nerve with erased contur while the MRI exam found a pineal gland tumor accompanied by triventricular hydrocephaly

Key words: vomiting, headache, pinealoma

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Corina Paul

TUMORA DE GLANDA PINEALA

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Corina Paul, Iulian Velea, Ionela Tămăşan, Carmen Postelnicu, Florin Bîrsăşteanu, Luiza Bădescu and Otilia Angi Cinca

REZUMAT

Tumorile de glandă pineală reprezintă 3-8% din totalul tumorilor cerebrale la copil. Vârsta medie de debut se situează între 10-13 ani. Simptomatologia clinică este în strânsă legătură atât cu relaţiile anatomice ale glandei pineale, cât şi cu structura histologică a formaţiunii tumorale. Cele mai frecvente simptome includ cefaleea, greţurile, vărsăturile, toate având ca substrat compresiunea pe structurile învecinate şi hidrocefalia consecutivă. Autorii prezintă cazul unei fetiţe în vârstă de 6 ani, internată în Clinica II Pediatrie pentru vărsături incoercibile, cefalee în cască. La examenul fundului de ochi se observă papila nervului optic cu contur şters iar examinarea RMN evidenţiază tumoră de glandă pineală cu hidrocefalie triventriculară.

Cuvinte cheie: vărsături, cefalee, pinealom

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Corina Paul

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