I. Velea, Corina Paul, Ionela Tămăşan, F. Bîrsăşteanu, Mirela Mogoi and Loredana Todorescu-Negru

ABSTRACT

The pituitary lies within the sella turcica and has a very important role in the regulation of the neuro-endocrine functions through its hormones. Prolactinoma represents a benign tumor of the pituitary (adenoma) which excesively produces the hormon called prolactin. The authors present the case of a male adolescent 16 years old, evaluated in the pediatrics ambulatory for height deficit. On this ocassion increased levels of prolactin were revealed. Later on the patient was admitted in Clinic II Pediatrics to complete investigation for diagnosis.

Key words: height defi cit, prolactin, growth hormone

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I. Velea, Corina Paul, Ionela Tămăşan, Loredana Todorescu-Negru, E. Boia, F. Bîrsăşteanu and D. Oneţ

ABSTRACT

Kallmann Syndrome is classically characterized by isolated GnRH deficit associated with hypo/anosmia. Clinically the patients presented micropenis, cryptorchidism, absence of puberty occurence, infertility. The paper presents the case of an adolescent aged 16, presenting anosmia and hypogonadism (observed by family) even since he was 3 years old. He was evaluated repeatedly in different medical services, but no clear diagnosis was made. Finally, the patient was admitted in Clinic II Pediatrics for investigations and diagnosis.

Key words: anosmia, hypogonadism, testosteron

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Corina Paul, I. Velea and Ionela Tămăşan

ABSTRACT

The metabolic syndrome (MS) represents a sum of risk factors leading to the occurence of cardio-vascular diseases and diabetes mellitus (DM). Of these factors we can mention: abdominal obesity, dyslipidemia, arterial hypertension, impaired glucose tolerance. That is why the early depistation of the children at risk to develop MS becomes extremely important. At the end of XXth century, the incidence of type 2 DM dramatically increased. This tendency to increase of type 2 DM prevalence in children is caused by an increase of obesity rate within the young individuals. Although the phyisio-pathological mechanisms of the MS are not clear yet, it seems that the insulin resistance has a key role. Actually, IR represents a disturbed response to the physiologic effects of insulin (affecting the metabolism of the carbohydrates, lipids and protein and also the function of the vascular endothelium). The paper presents the case of an adolescent girl, aged 13, with history of LGA (large for gestational age; birth weight = 5.040 g), with weight excess since she was a small child. The patient was addressed to Clinic II Pediatrics when beside weight excess she also associated high blood pressure.

Key words: metabolic syndrome, child, insulin resistance

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