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I. Velea

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Articole semnate de acelasi autor in Revista Romana de Pediatrie:

Height deficit associated to prolactinoma – case report

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Height deficit associated to prolactinoma – case report

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ABSTRACT

The pituitary lies within the sella turcica and has a very important role in the regulation of the neuro-endocrine functions through its hormones. Prolactinoma represents a benign tumor of the pituitary (adenoma) which excesively produces the hormon called prolactin. The authors present the case of a male adolescent 16 years old, evaluated in the pediatrics ambulatory for height deficit. On this ocassion increased levels of prolactin were revealed. Later on the patient was admitted in Clinic II Pediatrics to complete investigation for diagnosis.

Key words: height defi cit, prolactin, growth hormone

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KALLMANN Syndrome – case report

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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KALLMANN Syndrome – case report

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ABSTRACT

Kallmann Syndrome is classically characterized by isolated GnRH deficit associated with hypo/anosmia. Clinically the patients presented micropenis, cryptorchidism, absence of puberty occurence, infertility. The paper presents the case of an adolescent aged 16, presenting anosmia and hypogonadism (observed by family) even since he was 3 years old. He was evaluated repeatedly in different medical services, but no clear diagnosis was made. Finally, the patient was admitted in Clinic II Pediatrics for investigations and diagnosis.

Key words: anosmia, hypogonadism, testosteron

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DEFICIT STATURAL ASOCIAT PROLACTINOMULUI

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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DEFICIT STATURAL ASOCIAT PROLACTINOMULUI

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REZUMAT

Glanda hipofiză este situată la baza creierului, într-o formaţiune anatomică osoasă numită şaua turcească (sella turcica). Are un rol extrem de important în reglarea funcţiilor neuro-endocrine datorită hormonilor secretaţi. Prolactinomul reprezintă o tumoră benignă a glandei hipofize (adenom), ce produce în exces un hormon numit prolactina. Autorii prezintă cazul unui adolescent în vârstă de 16 ani, evaluat în ambulator pentru deficit staturo-ponderal, ocazie cu care s-au decelat valori crescute ale prolactinei serice. Ulterior, pacientul se internează în Clinica II Pediatrie pentru investigaţii suplimentare şi precizare de diagnostic.

Cuvinte cheie: deficit statural, prolactină, hormon de creştere

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SINDROM KALLMANN

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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SINDROM KALLMANN

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REZUMAT

Sindromul Kallmann se caracterizează prin deficit izolat de GnRH, asociat cu hipo/anosmie. La examenul clinic al pacienţilor cu sindrom Kallmann se decelează micropenis, criptorhidie, absenţa instalării pubertăţii, infertilitate. Se prezintă cazul unui adolescent în vârstă de 16 ani, afirmativ cu anosmie şi hipogonadism (sesizat de aparţinători) încă de la vârsta de 2-3 ani. A fost evaluat în repetate rânduri în diferite servicii medicale, fără a se stabili un diagnostic de certitudine. Ulterior, pacientul se internează în Clinica II Pediatrie pentru investigaţii suplimentare şi precizare de diagnostic.

Cuvinte cheie: anosmie, hipogonadism, testosteron

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Metabolic syndrome in an adolescent – case report

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Metabolic syndrome in an adolescent – case report

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ABSTRACT

The metabolic syndrome (MS) represents a sum of risk factors leading to the occurence of cardio-vascular diseases and diabetes mellitus (DM). Of these factors we can mention: abdominal obesity, dyslipidemia, arterial hypertension, impaired glucose tolerance. That is why the early depistation of the children at risk to develop MS becomes extremely important. At the end of XXth century, the incidence of type 2 DM dramatically increased. This tendency to increase of type 2 DM prevalence in children is caused by an increase of obesity rate within the young individuals. Although the phyisio-pathological mechanisms of the MS are not clear yet, it seems that the insulin resistance has a key role. Actually, IR represents a disturbed response to the physiologic effects of insulin (affecting the metabolism of the carbohydrates, lipids and protein and also the function of the vascular endothelium). The paper presents the case of an adolescent girl, aged 13, with history of LGA (large for gestational age; birth weight = 5.040 g), with weight excess since she was a small child. The patient was addressed to Clinic II Pediatrics when beside weight excess she also associated high blood pressure.

Key words: metabolic syndrome, child, insulin resistance

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SINDROMUL METABOLIC LA COPIL

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Revista Romana de PEDIATRIE | Volumul LX, Nr. 3, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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ICMJE- Recommendations

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SINDROMUL METABOLIC LA COPIL

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REZUMAT

Sindromul incisivului maxilar median unic este o afecţiune complexă, datorată unor defecte multiple de dezvoltare, în special pe linia mediană, secundar acţiunii unor factori necunoscuţi, care acţionează în zilele 35-38 de viaţă intrauterină. Autorii prezintă cazul copilului V.C. în vârstă de 13 ani 9 luni, cu repetate internări în vederea evaluării pentru hipostatură şi retard mental. La vârsta de 5 ani a fost diagnosticat cu astm bronşic, iar la vârsta de 10 ani cu panhipopituitarism; a urmat tratament de substituţie tiroidiană şi cu hormon de creştere, dar inconstant. Examenul clinic: retard statural marcat, facies dismorf, obstrucţie nazală cronică, prezenţa incisivului maxilar median unic, retard mental moderat, cu deficit de atenţie. Examinări paraclinice: CT cranian – hipoplazie hipofizară, determinările hormonale au confirmat diagnosticul de panhipopituitarism.

Cuvinte cheie: sindromul incisivului maxilar median unic, copil

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