National Awards “Science and Research”
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Metabolic syndrome in an adolescent – case report
Corina Paul, I. Velea and Ionela Tămăşan
The metabolic syndrome (MS) represents a sum of risk factors leading to the occurence of cardio-vascular diseases and diabetes mellitus (DM). Of these factors we can mention: abdominal obesity, dyslipidemia, arterial hypertension, impaired glucose tolerance. That is why the early depistation of the children at risk to develop MS becomes extremely important. At the end of XXth century, the incidence of type 2 DM dramatically increased. This tendency to increase of type 2 DM prevalence in children is caused by an increase of obesity rate within the young individuals. Although the phyisio-pathological mechanisms of the MS are not clear yet, it seems that the insulin resistance has a key role. Actually, IR represents a disturbed response to the physiologic effects of insulin (affecting the metabolism of the carbohydrates, lipids and protein and also the function of the vascular endothelium). The paper presents the case of an adolescent girl, aged 13, with history of LGA (large for gestational age; birth weight = 5.040 g), with weight excess since she was a small child. The patient was addressed to Clinic II Pediatrics when beside weight excess she also associated high blood pressure.
Key words: metabolic syndrome, child, insulin resistance