Romanian Journal of Pediatrics Logo
  • Home
  • Aims & Scope
  • Standards
    • Editorial policies
    • Instructions for authors
    • Peer review process
    • Guidelines for Reviewers
    • Ethics and Malpractice policies
    • Official Journal’s protocols & statements
    • Open Access
    • Fees
  • Editorial Council
  • Peer Review Council
  • EMC | CME
  • How to
  • SUBSCRIBE
  • Menu

Arhiva autor

  • About
  • Latest Posts

Maria Oana Marginean

Latest posts by Maria Oana Marginean (see all)

  • VENTRICULOMEGALIA CEREBRALA FETALA „BORDERLINE“ - 21/02/2017
  • FETAL CEREBRAL “BORDERLINE” VENTRICULOMEGALY - 21/02/2017
  • METAPLAZIA PANCREATICA A MUCOASEI GASTRICE LA COPIL - 03/11/2016

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

VENTRICULOMEGALIA CEREBRALA FETALA „BORDERLINE“

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

VENTRICULOMEGALIA CEREBRALA FETALA „BORDERLINE“

Claudiu Mărginean, Bela Szabo, Nicoleta Suciu, Lorena Melit, Andrada Ioana Crisan, Maria Oana Marginean and George Rolea

REZUMAT

Ventriculomegalia reprezintă dilatarea ventriculilor cerebrali peste 10 mm, fiind clasificată în uşoară sau „borderline“ (10-12 mm), moderată (13-15 mm) şi severă (peste 15 mm). Incidenţa variază foarte mult în funcţie de tehnica utilizată şi de vârsta gestaţională. Locul de elecţie pentru măsurarea cea mai exactă a diametrului ventricular este la nivelul glomusului plexului coroid. RMN-ul este o altă metodă de evaluare a creierului fetal care permite, de asemenea, vizualizarea suprafeţei cerebrale. Ventriculomegalia unilaterală este cauzată de obstrucţia morfologică, fizică sau funcţională a orificiului Monro. Ventriculomegalia „borderline“ poate fi asociată cu anomalii cromozomiale, infecţii congenitale, accidente vasculare cerebrale sau hemoragie, precum şi cu alte anomalii extracerebrale. Factori care influenţează prognosticul copiilor diagnosticaţi cu ventriculomegalie uşoară sunt: sexul, vârsta gestaţională, dimensiunea ventriculilor, afectarea uni- sau bilaterală, ventriculomegalie bilaterală simetrică sau asimetrică, progresia ventriculomegaliei – probabil cel mai important factor al prognosticului, regresia ventriculomegaliei. Părinţii trebuie informaţi despre faptul că există limitări ultrasonografice în diferenţierea unei ventriculomegalii „borderline“ izolate şi ventriculomegalie asociată unor altor anomalii oculte, care nu pot fi identificate iniţial în vederea luării unei decizii adecvate. Ecografia fetală de control este de preferat a se efectuat după aproximativ 1-2 săptămâni de la diagnosticul iniţial de „ventriculomegalie“.

Cuvinte cheie: ventriculomegalie, creier fetal, ultrasunete fetale, RMN cerebral

Full text | PDF

Claudiu Mărginean

FETAL CEREBRAL “BORDERLINE” VENTRICULOMEGALY

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

FETAL CEREBRAL “BORDERLINE” VENTRICULOMEGALY

Claudiu Mărginean, Bela Szabo, Nicoleta Suciu, Lorena Melit, Andrada Ioana Crisan, Maria Oana Marginean and George Rolea

ABSTRACT

Ventriculomegaly represents the dilation of the cerebral ventricles above 10 mm, being classified as it follows: mild or “borderline” (10-12 mm), moderate (13-15 mm) and severe (over 15 mm). The incidence varies very much depending on the used technique and the gestational age. The level of choice in order to obtain the most exact measurement of the ventricular diameter is at the level of choroid plexus glomus. The MRI is another method to assess the fetal brain that allows also the evaluation of the cerebral surface. Unilateral ventriculomegaly is caused by the morphologic, physical or functional obstruction of foramen Monro. “Borderline” ventriculomegaly can be associated with chromosomal anomalies, congenital infections, cerebral vascular accidents or hemorrhage, but also other extra-cerebral anomalies. The factors that influence the prognosis of children diagnosed with mild ventriculomegaly are: gender, gestational age, ventricular size, uni- or bilateral impairment, symmetrical or asymmentrical bilateral ventriculomegaly, progression of ventriculomegaly – probably the most important factor of prognosis, regression of ventriculomegaly. The parents must be informed about the fact that there are certain ultrasonographic limitations regarding the differentiation of an isolated “borderline” ventriculomegaly of a ventriculomegaly associated to other occult anomalies that can not be identified initially, in order to take an adequate decision. The control fetal ultrasound is preferable to be performed after approximately 1-2 weeks from the moment of initial diagnosis of “ventriculomegaly”.

Keywords: ventriculomegaly, fetal brain, fetal ultrasound, cerebral MRI

Full text | PDF

Claudiu Mărginean

METAPLAZIA PANCREATICA A MUCOASEI GASTRICE LA COPIL

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 3, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

METAPLAZIA PANCREATICA A MUCOASEI GASTRICE LA COPIL

Cristina Oana Mărginean, Lorena Elena Melit, Maria Oana Marginean, Nicoleta Suciu, Raluca Damian and Simona Mocan

REZUMAT

Metaplazia pancreatică este definită drept apariţia ţesutului pancreatic într-o locaţie anormală şi fară conectare directă la pancreas. Ţesutul pancreatic heterotopic este cel mai frecvent observat la nivelul mucoasei antrale gastrice, în duoden şi jejun. Prezentăm cazul unei paciente în vârstă de 13 ani care s-a internat în Clinica Pediatrie 1 Târgu-Mureş pentru dureri abdominale recurente şi pirozis. Investigaţiile de laborator efectuate au evidenţiat limfocitoză (41%) cu monocitoză (8,9%), eozinofilie (4,9%), un număr crescut de reticulocite (20%), un nivel seric scăzut al trigliceridelor şi o valoare peste limita superioară a calciului şi magneziului. Ecografia abdominală nu a pus în evidenţă modificări patologice. Endoscopia digestivă superioară a evidenţiat o mucoasă gastrică granulară. Astfel, s-a prelevat un fragment de biopsie de la nivel antral, iar examenul histopatologic a evidenţiat prezenţa unui focar de metaplazie pancreatică la nivelul mucoasei antrale gastrice. Evoluţia a fost favorabilă cu dietă şi tratamentul leziunilor asociate. Particularitatea cazului constă în prezenţa metaplaziei pancreatice a mucoasei gastrice la o pacientă cu dureri abdominale recurente şi pirozis, fără antecedente heredo-colaterale sau personale semnificative.

Cuvinte cheie: metaplazie pancreatică, copil, dureri abdominale, pirozis

Full text | PDF

Cristina Oana Mărginean

PANCREATIC METAPLASIA OF THE GASTRIC MUCOSA IN CHILD

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 3, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

PANCREATIC METAPLASIA OF THE GASTRIC MUCOSA IN CHILD

Cristina Oana Mărginean, Lorena Elena Melit, Maria Oana Marginean, Nicoleta Suciu, Raluca Damian and Simona Mocan

ABSTRACT

Pancreatic metaplasia is defined as the development of pancreatic tissue in an abnormal location and without direct connection to the pancreas. The heterotopic pancreatic tissue is most frequently noticed in the antral gastric mucosa, duodenum and jejunum. We present the case of a 13-year-old patient, admitted in Pediatrics Clinic 1 Targu-Mures, for recurrent abdominal pain and heartburns. The laboratory tests pointed out lymphocytosis (41%) with monocytosis (8.9%), eosinophilia (4.9%), an increased number of reticulocytes (20%), a decreased serum level of triglycerides and a value above the superior limit for calcium and magnesium. The abdominal ultrasound did not reveal any pathological modifications. The superior digestive endoscopy showed a granular gastric mucosa, therefore we took a biopsy of the antral mucosa, The pathological exam pointed out a fragment of pancreatic metaplasia in the antral gastric mucosa. The evolution was favorable with diet and treatment for the associated lesions. The particularity of the case consists in the presence of pancreatic metaplasia of the gastric mucosa in a patient with recurrent abdominal pain and heartburns, without significant familial or personal history.

Keywords: pancreatic metaplasia, child, abdominal pain, heartburn

Full text | PDF

Cristina Oana Mărginean

„KISSING-ULCER“ – DEBUT CU COMPLICATII LA VARSTA MICA

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 2, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

„KISSING-ULCER“ – DEBUT CU COMPLICATII LA VARSTA MICA

Andreea Dinca, Cristina Oana Mărginean, Lorena Elena Melit, Maria Oana Marginean and Raluca Damian

REZUMAT

Ulcerul este o patologie cu incidenţă scăzută la vârsta pediatrică, cu simptomatologie nespecifică sau chiar absentă, ducând astfel la apariţia complicaţiilor. Prezentăm cazul unui pacient în vârstă de 2 ani şi 10 luni, internat la spitalul de la nivel teritorial cu diagnosticul de gastroenterită acută febrilă, care în evoluţie (după 5 zile) a asociat hemoragie digestivă, impunând astfel transferul în Clinica de Pediatrie I, Târgu-Mureş. Endoscopia digestivă superioară, efectuată după reechilibrarea hemodinamică şi metabolică, a evidenţiat prezenţa a două ulcere la nivelul mucoasei duodenale, unul cu sângerare activă. Tratamentul cu inhibitori de pompă protonică şi dieta adecvată iniţiate au determinat evoluţia favorabilă a pacientului. Particularitatea cazului constă în apariţia a două ulcere duodenale la un copil de vârstă mică, fără antecedente personale patologice semnificative, cu condiţii de viaţă adecvate, fără factori de risc asociaţi şi fără infecţie cu Helicobacter pylori.

Cuvinte cheie: „kissing-ulcer“, copil, hemoragie digestivă superioară

Full text | PDF

Andreea Dinca

“KISSING-ULCER” – ONSET WITH COMPLICATIONS IN SMALL AGE

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 2, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

“KISSING-ULCER” – ONSET WITH COMPLICATIONS IN SMALL AGE

Lorena Elena Melit, Cristina Oana Mărginean, Raluca Damian, Maria Oana Marginean and Andreea Dinca

ABSTRACT

Ulcer disease is a pathology with low incidence in pediatric population, with an unspecific symptomatology or even absent, thus leading to the development of complications. We present the case of 2 years and 10 monthold male patient, admitted in the regional hospital with the diagnosis of febrile acute gastroenteritis, who in evolution (after 5 days) associated digestive hemorrhage, thus being transferred in the Pediatrics Clinic I, Targu-Mures. The superior digestive endoscopy performed after the hemodynamic and metabolic re-equilibration, pointed out 2 ulcers in the duodenal mucosa, one with active bleeding. The treatment with proton pump inhibitors and the adequate diet initiated determined the patient’s favorable evolution. The particularity of the case consists in the appearance of 2 duodenal ulcers of the duodenal mucosa in a small child, without significant personal history, with adequate life conditions, without associated risk factors and without infection with Helicobacter pylori.

Keywords: “kissing-ulcer”, child, superior digestive hemorrhage

Full text | PDF

Lorena Elena Melit

GASTROENTERITA ACUTA CU CLOSTRIDIUM DIFFICILE LA UN COPIL MIC CU INTOLERANTA EREDITARA LA LACTOZA

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 2, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

GASTROENTERITA ACUTA CU CLOSTRIDIUM DIFFICILE LA UN COPIL MIC CU INTOLERANTA EREDITARA LA LACTOZA

Andreea Dinca, Cristina Oana Mărginean, Lorena Elena Melit, Maria Oana Marginean and Raluca Damian

REZUMAT

Acute gastroenteritis with Clostridium difficile is insufficiently studied in the specialty literature due to its small incidence at this age, with increased rates of morbidity and mortality. We present the case of a 1 year and 10 month-old child, diagnosed with hereditary lactose intolerance in the neonatal period, admitted in the Pediatrics Clinic I, Targu-Mures, for vomiting, loss of appetite, decreased consistency stools, with a bed smell, with bacterial infection signs in the blood tests and slowly favorable evolution under treatment with cephalosporin. The patient is readmitted after 1 day from discharge with the reappearance of bad smell stools and loss of appetite, with unfavorable evolution after administering a 3rd generation cephalosporin, thus we raise the suspicion of infection with Clostridium difficile, confirmed by the identification of toxins in the stools, with favorable evolution under treatment for anaerobe germs (metronidazole). The particularity of the case consists in the development of a gastroenteritis with Clostridium difficile in a small child (1 year and 10 months), known with retardation in the neuro-psychomotor and language development, repeated episodes of hypoglycemia, with hereditary lactose intolerance which represented a challenge in establishing the diagnosis.

Cuvinte cheie: Clostridium difficile, child, gastroenteritis, hereditary lactose intolerance

Full text | PDF

Andreea Dinca

ACUTE GASTROENTERITIS WITH CLOSTRIDIUM DIFFICILE IN A SMALL CHILD WITH HEREDITARY LACTOSE INTOLERANCE

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 2, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

ACUTE GASTROENTERITIS WITH CLOSTRIDIUM DIFFICILE IN A SMALL CHILD WITH HEREDITARY LACTOSE INTOLERANCE

Andreea Dinca, Cristina Oana Mărginean, Lorena Elena Melit, Maria Oana Marginean and Raluca Damian

ABSTRACT

Acute gastroenteritis with Clostridium difficile is insufficiently studied in the specialty literature due to its small incidence at this age, with increased rates of morbidity and mortality. We present the case of a 1 year and 10 month-old child, diagnosed with hereditary lactose intolerance in the neonatal period, admitted in the Pediatrics Clinic I, Targu-Mures, for vomiting, loss of appetite, decreased consistency stools, with a bed smell, with bacterial infection signs in the blood tests and slowly favorable evolution under treatment with cephalosporin. The patient is readmitted after 1 day from discharge with the reappearance of bad smell stools and loss of appetite, with unfavorable evolution after administering a 3rd generation cephalosporin, thus we raise the suspicion of infection with Clostridium difficile, confirmed by the identification of toxins in the stools, with favorable evolution under treatment for anaerobe germs (metronidazole). The particularity of the case consists in the development of a gastroenteritis with Clostridium difficile in a small child (1 year and 10 months), known with retardation in the neuro-psychomotor and language development, repeated episodes of hypoglycemia, with hereditary lactose intolerance which represented a challenge in establishing the diagnosis.

Keywords: Clostridium difficile, child, gastroenteritis, hereditary lactose intolerance

Full text | PDF

Andreea Dinca

LIMFOMUL BURKITT – PERSEVERENTA CLINICIANULUI IN STABILIREA DIAGNOSTICULUI

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

LIMFOMUL BURKITT – PERSEVERENTA CLINICIANULUI IN STABILIREA DIAGNOSTICULUI

Lorena Elena Melit, Oana Cristina Marginean, Mihaela Chincesan, Andreea Dinca, Raluca Damian and Maria Oana Marginean

REZUMAT

Limfomul Burkitt, subtip al limfoamelor non-Hodgkin, apare cu predilecţie la vârstele mici şi prezintă cea mai rapidă creştere tumorală întâlnită la oameni. Prezentăm cazul unui copil în vârstă de 5 ani, cu dureri abdominale difuze, distensie abdominală şi scaune semiconsistente, este transferat în Clinica Pediatrie I Târgu-Mureş, cu diagnosticul de malnutriţie severă şi edeme hipoproteice, de etiologie neprecizată. Investigaţiile de laborator efectuate arată leucocitoză, VSH uşor crescut, anemie, nivel scăzut al proteinelor plasmatice, precum şi nivel crescut al LDH-ului. Ecografia abdominală pune în evidenţă lichid intraabdominal, iar CT-ul abdominal arată lichid liber între ansele intestinale, 2 fistule, una duodeno-colică şi una jejuno-colică, precum şi andenopatii. Surpriza intraoperatorie este descoperirea unei mase tumorale care implică duodenul, jejunul şi colon, iar examenul histopatologic stabileşte diagnosticul de limfom Burkitt, formă extranodală, cu evoluţie post-operatorie grevată de multiple complicaţii. După a treia reintervenţie chirurgicală, se iniţiază chimioterpia. Deşi uneori tabloul clinic nu este sugestiv pentru severitatea patologiei, perseverenţa clinicianului este cea care duce în final la stabilirea diagnosticului.

Cuvinte cheie: limfom Burkitt, copil, diagnostic.

Full text | PDF

Lorena Elena Melit

BURKITT LYMPHOMA – CLINICIANS’S PERSEVERANCE IN ESTABLISHING THE DIAGNOSIS

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

BURKITT LYMPHOMA – CLINICIANS’S PERSEVERANCE IN ESTABLISHING THE DIAGNOSIS

Lorena Elena Melit, Oana Cristina Marginean, Mihaela Chincesan, Andreea Dinca, Raluca Damian and Maria Oana Marginean

ABSTRACT

Burkitt lymphoma, a subtype of non-Hodgkin lymphomas, appears especially in small ages and it presents the most rapid tumor growth encountered in the human beings. We present the case of a 5 year-old child who presents diffuse, abdominal pain, abdominal distension and decreased consistency stools, and who is transferred in the Pediatrics Clinic 1 Targu-Mures, with the diagnosis of severe malnutrition and hypoproteinemia edema of unknown etiology. The laboratory investigations performed showed leukocytosis, mildly increased erythrocyte sedimentation rate, anemia, decreased level of serum proteins, and also an increased level of LDH. The abdominal ultrasound revealed intraperitoneal fluid, and the abdominal CT exam showed free fluid between the intestinal loops, 2 fistulas, one between the duodenum and the colon, and the other one between the jejunum and the colon, but also enlarged lymph nodes. The surprise during the surgery is the discovery of a tumor mass which involves the duodenum, the jejunum and the colon, and the pathological exam establishes the diagnosis of Burkitt lymphoma, extranodal type, with evolution after surgery burdened by multiple complications. After the third surgical intervention, the chemotherapy is initiated. Even though in some cases, the clinical picture is not suggestive for the severity of the pathology, the clinician’s perseverance is the one that finally leads to the establishment of the diagnosis.

Keywords: Burkitt lymphoma, child, diagnosis.

Full text | PDF

Lorena Elena Melit

Post navigation

1 2 Next »


SEARCH

STANDARDE

  • Instructions for authors
  • Peer review process

Submit article

Submit your article to the journal by using the form here:

Submit

Subscriptions

To receive the Ro Journal of PEDIATRICS click here:

SUBSCRIBE
Publicare-RRPedia
Abonare_RRPedia

Partners

Partners logo

plic-maileditor@rjp.com.ro

Subscribe to the Newsletter

Articles from the journal are licensed under a 
Creative Commons Attribution 4.0 International License

 Terms & Conditions

Open Access Statement

Publisher : AMALTEA Medical Publishing House

The intended audience of the site content is professionals from the medical and pharmaceutical community.
This site does not collect any personal data nor does it use cookies that might obtain such data from your browser. [ info ]
Agree
Contact

Submit ARTICLE
E-mail: editor@rjp.com.ro  |  Mobile: +4 0742.155.512, M-F 09.00-18.00 EET

SUBSCRIPTIONS
E-mail: info@amaltea.ro |  Mobile: +4 0742.155.511, M-F 09.00-18.00 EET