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Oana Cristina Marginean

Latest posts by Oana Cristina Marginean (see all)

  • LIMFOMUL BURKITT – PERSEVERENTA CLINICIANULUI IN STABILIREA DIAGNOSTICULUI - 05/07/2016
  • BURKITT LYMPHOMA – CLINICIANS’S PERSEVERANCE IN ESTABLISHING THE DIAGNOSIS - 05/07/2016
  • ANEMIA APLASTICA – ASPECTE TERAPEUTICE SI DEONTOLOGICE - 04/07/2016

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

LIMFOMUL BURKITT – PERSEVERENTA CLINICIANULUI IN STABILIREA DIAGNOSTICULUI

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

LIMFOMUL BURKITT – PERSEVERENTA CLINICIANULUI IN STABILIREA DIAGNOSTICULUI

Lorena Elena Melit, Oana Cristina Marginean, Mihaela Chincesan, Andreea Dinca, Raluca Damian and Maria Oana Marginean

REZUMAT

Limfomul Burkitt, subtip al limfoamelor non-Hodgkin, apare cu predilecţie la vârstele mici şi prezintă cea mai rapidă creştere tumorală întâlnită la oameni. Prezentăm cazul unui copil în vârstă de 5 ani, cu dureri abdominale difuze, distensie abdominală şi scaune semiconsistente, este transferat în Clinica Pediatrie I Târgu-Mureş, cu diagnosticul de malnutriţie severă şi edeme hipoproteice, de etiologie neprecizată. Investigaţiile de laborator efectuate arată leucocitoză, VSH uşor crescut, anemie, nivel scăzut al proteinelor plasmatice, precum şi nivel crescut al LDH-ului. Ecografia abdominală pune în evidenţă lichid intraabdominal, iar CT-ul abdominal arată lichid liber între ansele intestinale, 2 fistule, una duodeno-colică şi una jejuno-colică, precum şi andenopatii. Surpriza intraoperatorie este descoperirea unei mase tumorale care implică duodenul, jejunul şi colon, iar examenul histopatologic stabileşte diagnosticul de limfom Burkitt, formă extranodală, cu evoluţie post-operatorie grevată de multiple complicaţii. După a treia reintervenţie chirurgicală, se iniţiază chimioterpia. Deşi uneori tabloul clinic nu este sugestiv pentru severitatea patologiei, perseverenţa clinicianului este cea care duce în final la stabilirea diagnosticului.

Cuvinte cheie: limfom Burkitt, copil, diagnostic.

Full text | PDF

Lorena Elena Melit

BURKITT LYMPHOMA – CLINICIANS’S PERSEVERANCE IN ESTABLISHING THE DIAGNOSIS

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

BURKITT LYMPHOMA – CLINICIANS’S PERSEVERANCE IN ESTABLISHING THE DIAGNOSIS

Lorena Elena Melit, Oana Cristina Marginean, Mihaela Chincesan, Andreea Dinca, Raluca Damian and Maria Oana Marginean

ABSTRACT

Burkitt lymphoma, a subtype of non-Hodgkin lymphomas, appears especially in small ages and it presents the most rapid tumor growth encountered in the human beings. We present the case of a 5 year-old child who presents diffuse, abdominal pain, abdominal distension and decreased consistency stools, and who is transferred in the Pediatrics Clinic 1 Targu-Mures, with the diagnosis of severe malnutrition and hypoproteinemia edema of unknown etiology. The laboratory investigations performed showed leukocytosis, mildly increased erythrocyte sedimentation rate, anemia, decreased level of serum proteins, and also an increased level of LDH. The abdominal ultrasound revealed intraperitoneal fluid, and the abdominal CT exam showed free fluid between the intestinal loops, 2 fistulas, one between the duodenum and the colon, and the other one between the jejunum and the colon, but also enlarged lymph nodes. The surprise during the surgery is the discovery of a tumor mass which involves the duodenum, the jejunum and the colon, and the pathological exam establishes the diagnosis of Burkitt lymphoma, extranodal type, with evolution after surgery burdened by multiple complications. After the third surgical intervention, the chemotherapy is initiated. Even though in some cases, the clinical picture is not suggestive for the severity of the pathology, the clinician’s perseverance is the one that finally leads to the establishment of the diagnosis.

Keywords: Burkitt lymphoma, child, diagnosis.

Full text | PDF

Lorena Elena Melit

ANEMIA APLASTICA – ASPECTE TERAPEUTICE SI DEONTOLOGICE

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

ANEMIA APLASTICA – ASPECTE TERAPEUTICE SI DEONTOLOGICE

Andreea Ligia Dinca, Oana Cristina Marginean, Lorena Elena Melit, Raluca Damian and Mihaela Chincesan

REZUMAT

Anemia aplastică este o patologie hematologică severă, potenţial fatală, caracterizată prin citopenie periferică şi măduvă osoasă hipocelulară, cu o prevalenţă de 2-6 cazuri la 1 milion locuitori. Prezentarea actuală ilustrează cazul unui copil de 9 ani, fără antecedente personale patologice cunoscute, şi cu debut brusc, aparent în plină stare de sănătate, diagnosticat cu anemie aplastică idiopatică severă şi cu evoluţie fulminantă. Lipsa de complianţă a părinţilor la actul medical, precum şi lipsa unei legislaţii care să protejeze copilul, au dus la decesul pa cientului într-un interval foarte scurt de timp.

Cuvinte cheie: copil, pancitopenie, anemie aplastică

Full text | PDF

Andreea Ligia Dinca

APLASTIC ANAEMIA – THERAPEUTIC AND DEONTOLOGICAL ASPECTS

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

APLASTIC ANAEMIA – THERAPEUTIC AND DEONTOLOGICAL ASPECTS

Andreea Ligia Dinca, Oana Cristina Marginean, Lorena Elena Melit, Raluca Damian and Mihaela Chincesan

ABSTRACT

Aplastic Anaemia is a severe potentially fatal haematological syndrome, characterised by peripheral pancytopenia and bone marrow hypoplasia, with an occurrence rate of 2-6 cases per million per year. This case report is about a 9 year-old boy, with no pathological known antecedents, and a sudden onset, apparently without any pathological associated conditions, who was diagnosed with severe Idiopathic Aplastic Anaemia, and a fulminate evolution. The lack of compliance of the parents regarding the therapy, and also the lack of a protective child’s legislation, led to patient’s death in a very short time.

Keywords: child, pancytopenia, aplastic anaemias

Full text | PDF

Andreea Ligia Dinca


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