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Mihaela-Ioana Chincesan

Latest posts by Mihaela-Ioana Chincesan (see all)

  • TIMOMUL: O CAUZA RARA DE TUMORA MEDIASTINALA LA COPIL - 22/02/2017
  • THYMOMA: A RARE CAUSE OF MEDIASTINAL TUMOR IN CHILDREN - 22/02/2017
  • DATE ANTROPOMETRICE SI DE BIOIMPEDANTA ELECTRICA LA UN GRUP DE PACIENTI PEDIATRICI CU LEUCEMII - 20/07/2015

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

TIMOMUL: O CAUZA RARA DE TUMORA MEDIASTINALA LA COPIL

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Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

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TIMOMUL: O CAUZA RARA DE TUMORA MEDIASTINALA LA COPIL

Andreea Durlan, Cristina Oana Mărginean, Maria Despina Baghiu, Alina Grama, Emoke Horvath and Mihaela-Ioana Chincesan

REZUMAT

Timomul este un neoplasm format din celule epiteliale timice, fiind rar întâlnit la copii. Aproximativ două treimi din tumorile mediastinale sunt asimptomatice la copii, diagnosticul fiind suspicionat în urma efectului de compresie a masei tumorale asupra căilor respiratorii. Prezentăm cazul unui pacient de sex masculin, în vârstă de 7 ani şi 8 luni, care se prezintă în serviciul de urgenţă acuzând oboseală la eforturi mici/repaus, tuse seacă, dispnee marcată, ortopnee, tahipnee, durere toracică, de unde se transferă de urgenţă la Clinica de Cardiologie Pediatrică, Tîrgu Mureş, cu diagnosticele: pericardită lichidiană, tamponadă cardiacă şi pleurezie dreaptă. Examenul computer tomografic toracic descrie o masă solidă inomogenă de 100/89/111 mm, la nivelul mediastinului anterior înglobând timusul şi parţial structurile vasculare ale mediastinului mijlociu. Se practică pericardectomie parţială, prelevare de ţesut tumoral şi citoreducţie tumorală extensivă, examenul histopatologic fiind Timom B3. Se iniţiază chimioterapie conform protocolului VENUTA Tymom, urmat de radioterapie adjuvantă, cu remisie clinică şi radiologică. Particularitatea cazului este dată de faptul că timomul este o tumoră rară la vârsta pacientului, creând dificultăţi de diagnostic, fiind fără complicaţii în timpul tratamentului, cu evoluţie favorabilă, cu remisie clinică şi radiologică la 1,9 ani.

Cuvinte cheie: copil, timom, tumoră mediastinală

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Andreea Durlan

THYMOMA: A RARE CAUSE OF MEDIASTINAL TUMOR IN CHILDREN

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

THYMOMA: A RARE CAUSE OF MEDIASTINAL TUMOR IN CHILDREN

Andreea Durlan, Cristina Oana Mărginean, Maria Despina Baghiu, Alina Grama, Emoke Horvath and Mihaela-Ioana Chincesan

ABSTRACT

Thymoma is a thymic neoplasm composed of epithelial cells, rarely seen in children. Approximately two-thirds of mediastinal tumors in children are asymptomatic. The diagnosis is suspected following the compression of the tumor mass on the airways. We present the case of a male patient, age 7 years and 8 months, who presented at the emergency room accusing fatigue at rest or minimum effort, dry cough, intense dyspnea, orthopnea, tachypnea, chest pain, being transferred to the Pediatric Cardiology Clinic in Tirgu Mures with the following diagnoses: fluid pericarditis, right pleural effusion and cardiac tamponade. Chest computer tomography examination is carried out, describing a solid mass of 100/89/111 mm in the anterior mediastinum, partially incorporating the thymus and the vascular structures of the middle mediastinum. Pericardectomy is practiced with partial removal of the tumor and extensive tumor cytoreduction and the histopathologic examination is B3 Thymoma. Specific treatment is initiated according to the Tymoma VENUTA protocol, followed by adjuvant radiotherapy, with clinical and radiological remission. The particularity of the case is the fact that thymoma is a rare tumor on the patient’s age, creating diagnostic difficulties, has no complications during treatment, with favorable evolution, with clinical and radiological remission at 1.9 years after.

Keywords: child, thymoma, mediastinal tumor

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Andreea Durlan

DATE ANTROPOMETRICE SI DE BIOIMPEDANTA ELECTRICA LA UN GRUP DE PACIENTI PEDIATRICI CU LEUCEMII

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Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 2, An 2014
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

DATE ANTROPOMETRICE SI DE BIOIMPEDANTA ELECTRICA LA UN GRUP DE PACIENTI PEDIATRICI CU LEUCEMII

Mihaela-Ioana Chincesan, Alina Grama, Gabriela Florian and Oana Marginean

REZUMAT

Introducere. Statusul nutriţional precar este o problemă comună în rândul copiilor cu afecţiuni oncologice. În scopul de a detecta modificările statusului nutriţional şi ale compoziţiei corporale, acest studiu investighează parametrii antropometrici şi compoziţia corporală la pacienţii pediatrici cu leucemie.

Material şi metodă. Studiul de tip prospectiv a inclus 33 de pacienţi internaţi în Clinica Pediatrie I Târgu-Mureş împărţiţi în două loturi: lotul I – lot studiu, pacienţi cu leucemie (15 copii) şi lotul II – lot control, pacienţi cu afecţiuni pediatrice (18 copii). S-au măsurat parametrii antropometrici (greutatea – G, înălţimea – I, indicele de masă corporală – BMI, perimetrul mediu al braţului – MUAC şi pliul cutanat tricipital – TST), iar cu ajutorul Analizorului Tanita BC 420 S MA s-a determinat ţesutul gras (FM – kg şi %), ţesutul non-gras (FFM – kg), masa musculară (MM – kg) şi procentul de apă totală din corp (TBW – %).

Rezultate. Parametrii antropometrici la lotul de studiu a diferit semnificativ statistic faţă de lotul martor pentru MUAC şi TST (p < 0,05). La copiii din lotul de studiu, FM a fost mult mai redus (14,79 ± 7,14%) comparativ cu lotul martor (21,56 ± 9,06 %) (p = 0,01), iar TBW mai mare (61,84 ± 4,93% versus 57,45 ± 6,64%) (p = 0,02). FFM şi MM nu au diferit statistic la cele două loturi.

Concluzii. BIA, alături de antropometria braţelor, este o metodă sensibilă în detectarea alterării compoziţiei corporale la copiii cu malignitate. Comparativ cu lotul de copii cu boli non-maligne, copiii cu leucemii au prezentat alterări mai marcate ale statusului nutriţional.

Cuvinte cheie: bioimpedanţă electrică, antropometrie, copii, leucemie

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Mihaela-Ioana Chincesan

ANTROPOMETRIC AND BIOIMPEDANCE DATA IN A GROUP OF PEDIATRIC PATIENTS WITH LEUKEMIA

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 2, An 2014
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

ANTROPOMETRIC AND BIOIMPEDANCE DATA IN A GROUP OF PEDIATRIC PATIENTS WITH LEUKEMIA

Mihaela-Ioana Chincesan, Alina Grama, Gabriela Florian and Oana Marginean

ABSTRACT

Introduction. Poor nutritional status is a common problem among children with malignant disease. In order to detect changes in nutritional status and body composition this study investigates anthropometrical parameters and body composition among pediatric patients with leukemia.

Material and methods. The prospective study included 33 patients hospitalized in Pediatric Clinic No I TgMures who were divided in two groups: group I-study group, patients with leukemia (15 patients) and group IIthe control group consisting of 18 patients with different pediatric diseases. The anthropometric parameters [weight-W, height-H, body mass index (BMI), middle upper arm circumference (MUAC), tricipital skinfold thickness (TST)] were comparatively evaluated. Fat mass (FM, kg and %), fat free mass (FFM, kg), muscle mass (MM, kg) and total body water (TBW, %) were measured in the both group using Tanita BC 420 S MA Analyzer.

Results. Anthropometric parameters in Group I were significantly different from those in Group II for MUAC and TST (p < 0.05). In the study group, FM was much lower (14.79 ± 7.14%) compared with controls (21.56 ± 9.06%) (p = 0.01) and TBW was much higher (61.84 ± 4.93% versus 57.45 ± 6.64%) (p = 0.02). FFM and MM were not statistically different in the two groups.

Conclusion. Bioelectrical impedance analysis in conjunction with arm anthropometry is a sensitive method to detect alteration of body composition in children with malignancy. Compared with the control group, children with leukemia had higher alterations of nutritional status

Keywords: electrical bioimpedance, anthropometry, children, leukemia

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Mihaela-Ioana Chincesan


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