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Georgiana Russu

Latest posts by Georgiana Russu (see all)

  • ASPECTE PSIHOLOGICE SI ETICE LEGATE DE PREZENTA MEMBRILOR FAMILIEI IN TIMPUL RESUSCITARII CARDIACE LA COPIL - 21/02/2017
  • PSYCHOLOGICAL AND ETHICAL ASPECTS OF THE PRESENCE OF FAMILY MEMBERS DURING CARDIAC RESUSCITATION IN CHILDREN - 21/02/2017
  • PERTURBAREA AUZULUI – COMPONENTA A SINDROMULUI ALCOOL FETAL - 29/08/2016

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

The child with cardiac pathology in the family doctor’s office

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 2, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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The child with cardiac pathology in the family doctor’s office

Georgiana Russu

ABSTRACT

The congenital or acquired heart disease offers to the child a place in the top of the list with chronic diseases, with the wrights to obtain medical care from a team composed by family doctor, pediatric cardiologist, heart surgeon, nutrition specialist and psychologist. The family doctor has to discover the cardiopathy, to put on a special list the child previously diagnosed, and to ensure the basic care. These depend on the severity of the cardiac disease, the age of the patient, the risks of complications or the vital risk by acquired comorbidities (infections, malnutrition, psychoreactive reactions). The protocol of medical care specific for every cardiac disease established by the pediatric cardiologist must be adapted during the evolution of the disease by a continuous collaboration between the family doctor and the pediatric cardiologist. The problem is more and more complex because the increase of the survival chances of these children thanks to the progresses in diagnosis and medical or surgical treatment.

Key words: heart disease, child, family doctor

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Georgiana Russu

COPILUL CU PATOLOGIE CARDIACA IN CABINETUL MEDICULUI DE FAMILIE

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 2, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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COPILUL CU PATOLOGIE CARDIACA IN CABINETUL MEDICULUI DE FAMILIE

Georgiana Russu

REZUMAT

Cardiopatia congenitală sau dobândită poziţionează copilul pe un loc prioritar în lista bolnavilor cu boli cronice, cu dreptul de a beneficia de o îngrijire în echipă: medic de familie – pediatru cardiolog – chirurg cardiolog – nutriţionist – psiholog. Medicul de familie este implicat în depistarea cardiopatiei, în trecerea în evidenţă specială a unui copil diagnosticat anterior şi în asigurarea îngrijirilor de bază. Aceste îngrijiri sunt nuanţate de gravitatea cardiopatiei, vârsta bolnavului, riscurile de complicaţii ale cardiopatiei sau riscurile vitale prin comorbidităţi dobândite (infecţii, malnutriţie, tulburări psihoreactive). Protocolul de îngrijiri specifice cardiopatiei alcătuit de pediatrul cardiolog trebuie adaptat în dinamica evoluţiei cazului prin colaborare continuă între medicul de familie şi medicul cardiolog pediatru. Problema devine tot mai complexă prin creşterea şanselor de supravieţuire a copiilor cu cardiopatii graţie progreselor diagnosticului şi tratamentelor conservatoare sau chirurgicale.

Cuvinte cheie: malformaţie cardiacă, copil, medic de familie

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Georgiana Russu

DUREREA NON-ORGANICA SI HIPERALGEZIA VISCERALA LA COPIL

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 4, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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DUREREA NON-ORGANICA SI HIPERALGEZIA VISCERALA LA COPIL

Ileana Ioniuc, Monica Alexoae and Georgiana Russu

REZUMAT

Durerea viscerală are particularităţi faţă de cea somatică: receptorii viscerali au grade diferite de angajare funcţională, nivelul nocicepţiei diferă de la un organ la altul, aferenţele viscerale puţine sunt predominant nemielinizate şi au o divergenţă extensivă la nivelul sistemului nervos central; răspunsurile antrenează activări auto nomice. Matricea durerii viscerale abdominale, funcţională la naştere, este suprasolicitată prin impulsuri me canice, chimice, osmotice; suprapunerea infecţiilor, inflamaţiilor prin mediatorii eliberaţi creează condiţiile „sensi bilizării“ periferice şi centrale şi ale dobândirii „memoriei durerii“; factori comportamentali şi emoţionali pot agrava hiperactivitatea matricei durerii viscerale. În acest context patogenetic se delimitează durerea no norganică şi forma ei severă, hiperalgezia viscerală. Se adaugă particularităţi genetice care influenţează pragul de sensibilitate la durere. Având la bază modelele biopsihosociale ale tulburărilor funcţionale, criteriile Roma III au etichetat durerile abdominale funcţionale şi sindromul de intestin iritabil ca posibile diagnostice directe şi nu doar diagnostice de excludere. Durerea non-organică, asociată frecvent cu dureri abdominale recurente, este printre cele mai frecvente probleme medicale întâlnite în pediatrie. Majoritatea pacienţilor cu dureri uşoare au o evoluţie favorabilă în timp; un procent redus prezintă simptome grave şi uneori dizabilitante. Pediatrii se confruntă frecvent cu delimitarea diagnosticului de durere non-organică şi, uneori, cu eşecuri terapeutice. Autorii prezintă date epidemiologice, mecanismele fiziopatologice implicate, abordarea clinică şi opţiunile terapeutice cu privire la durerea nonorganică şi hiperalgezia viscerală la copii şi adolescenţi.

Cuvinte cheie: durere abdominală funcţională, hiperalgezie viscerală, copil

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Ileana Ioniuc

NONORGANIC PAIN AND VISCERAL HYPERALGESIA IN CHILDHOOD

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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 4, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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NONORGANIC PAIN AND VISCERAL HYPERALGESIA IN CHILDHOOD

Ileana Ioniuc, Monica Alexoae and Georgiana Russu

ABSTRACT

Visceral pain is different from the somatic one: visceral receptors have different functional engagement, the nociception degree differ from one organ to another, the few visceral afferent fibers are predominantly unmyelinised and have an extensive divergence in the central nervous system; the responses involve autonomic activation. The matrix of abdominal visceral pain, functional at birth, is overburdened by mechanical, chemical, osmotic impulses; overlapping infections or inflammation, by the released mediators create the conditions for acquiring the peripheral and central “sensibility” and the “pain memory”; behavioral and emotional factors can aggravate the visceral pain matrix hyperreactivity. In this pathogenic context it defines nonorganic pain and its severe form, visceral hyperalgesia. Genetic peculiarities influence the pain sensitivity. Based on the biopsychosocial model of functional disorders, Rome III criteria tagged the abdominal functional pain and the irritable bowel syndrome as a positive diagnosis and not a diagnosis of exclusion. Nonorganic pain, often associated with recurrent abdominal pain is among the most common medical problems encountered in pediatrics. Most patients with mild pain have a good evolution over time; a small percentage present serious and sometimes disabling symptoms. Pediatricians frequently have difficulties in delineation the diagnosis of nonorganic pain and that, sometimes, involves treatment failure. The authors present the epidemiological data, the pathophysiological mechanisms involved, the clinical approach and the therapeutic options on nonorganic pain and visceral hyperalgesia in children.

Key words: functional abdominal pain, visceral hyperalgesia, child

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Ileana Ioniuc

BIOPROTEZA VALVULARA MITRALA DEGENERATA PRECOCE

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Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 3, An 2014
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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BIOPROTEZA VALVULARA MITRALA DEGENERATA PRECOCE

Irina-Mihaela Ciomaga, Georgiana Russu, Cristina Jitareanu, Violeta Streanga, Aniela Rugina and Nicolai Nistor

REZUMAT

Prolapsul de valvă mitrală (PVM) este destul de frecvent întâlnit la copil, fi ind deseori o descoperire întâmplătoare la un copil asimptomatic, dar şi la copii simptomatici, cu boli ale ţesutului conjunctiv. Autorii raportează cazul unei fetiţe de 11 ani, diagnosticată la vârsta de 6 ani cu insufi cienţă mitrală severă prin prolaps de valvă mitrală şi operată la vârsta de 7 ani, când s-a practicat înlocuirea valvei mitrale cu o proteză valvulară biologică. La 4 ani de la protezarea valvulară, fetiţa se prezintă în urgenţă pentru instalarea bruscă a dispneei cu ortopnee, hemoptiziei şi cianozei generalizate. Examenul clinic corelat cu ecocardiografi a au stabilit diagnosticul de edem pulmonar acut şi proteză biologică valvulară degenerată, cu stenoză mitrală severă. Evoluţia a fost favorabilă după înlocuirea în urgenţă a bioprotezei cu o proteză mecanică.

Cuvinte cheie: bioproteză, valvă mitrală, copil

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Irina-Mihaela Ciomaga

EARLY DEGENERATED BIOPROSTHETIC MITRAL VALVE

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Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 3, An 2014
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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EARLY DEGENERATED BIOPROSTHETIC MITRAL VALVE

Irina-Mihaela Ciomaga, Georgiana Russu, Cristina Jitareanu, Violeta Streanga, Aniela Rugina and Nicolai Nistor

ABSTRACT

Mitral valve prolapse (MVP) is fairly common in children, often being randomly found in asymptomatic, as well as in symptomatic patients with conjunctive tissue diseases (CTD). The authors report the case of an 11-yearold girl, diagnosed at the age of 6 with MVP and severe mitral regurgitation (MR). She had surgery at the age of seven, when the mitral valve replacement with a biological valve prosthesis was performed. Four years later, the girl was admitted for sudden onset of dyspnoea with orthopnoea, haemoptysis and generalized cyanosis. The diagnosis of acute pulmonary oedema and degenerated biological valvular prosthesis correlated with severe mitral stenosis was evoked by means of clinical and echocardiographic examinations. The evolution was favourable after the replacement of the bioprosthesis with a mechanical prosthesis.

Keywords: bioprosthesis, mitral valve, child

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Irina-Mihaela Ciomaga

ETICA PRESCRIERII OFF-LABEL A MEDICAMENTELOR LA COPII. DILEMA SILDENAFILULUI

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Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 2, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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ETICA PRESCRIERII OFF-LABEL A MEDICAMENTELOR LA COPII. DILEMA SILDENAFILULUI

Laszlo-Zoltan Sztankovszky, Magdalena Iorga, Cristian Gheonea and Georgiana Russu

REZUMAT

Prescripţia „off-label“ reprezintă administrarea medicamentelor pe o cale neaprobată, într-o formulare sau doză neaprobată la copii, sau sub intervalul de vârstă indicat pe prospectul aprobat al produsului. Cu toate acestea, tratamentul cu indicaţii off-label este un fenomen larg răspândit în clinicile de pediatrie. Deoarece multe dintre medicamentele prescrise nu au fost testate în mod adecvat la copii, această populaţie de pacienţi rămâne vulnerabilă. Pe de o parte, folosirea indicaţiilor off-label la copii determină o mulţime de controverse, pe de altă parte, fără această posibilitate, unii pacienţi ar putea fi lipsiţi de şansa de a fi trataţi. Lucrarea prezintă amplitudinea fenomenului de prescriere a medicamentelor cu indicaţii off-label la copii, evaluată în studii ştiinţifice din SUA şi Europa. În multitudinea de medicamente prescrise off-label la copii se înscrie şi Sildenafil. Autorii îşi propun prezentarea situaţiei din România cu privire la medicamentul Sildenafil şi utilizarea acestuia în unităţile de cardiologie pediatrică.

Cuvinte cheie: etica, medicamente, copii, prescriere, off-label

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Laszlo-Zoltan Sztankovszky

THE ETHICS OF PRESCRIBING OFF-LABEL DRUGS IN CHILDREN. THE DILEMMA OF SILDENAFIL

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Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 2, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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THE ETHICS OF PRESCRIBING OFF-LABEL DRUGS IN CHILDREN. THE DILEMMA OF SILDENAFIL

Laszlo-Zoltan Sztankovszky, Magdalena Iorga, Cristian Gheonea and Georgiana Russu

ABSTRACT

The off-label prescription means that medicines are administered by an unlicensed route, in an unlicensed formulation or dosage or to a child below the stated age range. The use of drugs in an off-label or unlicensed manner to treat children is widespread. Because many prescribed treatments for children have not been adequately tested in children, this population of patients remains a vulnerable one. On the one hand, prescribing off-label use drugs in children determines a lot of controversies but, one the other hand, without this possibility, could be deprived of a chance to be treated. The paper presents the widespread phenomenon of off-label us drugs in children, reflecting in scientific studies in USA and Europe. An important focus is on Romanian statistic of Sildenafil prescription and on dilemmatic use of it in pediatric cardiology unit.

Keywords: ethics, drugs, children, prescribing, off-label

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Laszlo-Zoltan Sztankovszky

OSTEOPENIA IN COPILARIE SI ADOLESCENTA

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Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 4, An 2014
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Promoting Global Health

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OSTEOPENIA IN COPILARIE SI ADOLESCENTA

Georgiana Russu, Tania Rusu, Ileana Ioniuc and Stela Gotia

REZUMAT

Osteopenia, termen aparţinând patologiei copilului, este o scădere a masei osoase în raport cu vârsta cronologică, reprezentând o stare intermediară între normal şi osteoporoză. Este o afecţiune plurietiologică, cu prinzând un grup heterogen de boli ale ţesutului conjunctiv cu determinism genetic, dar şi osteopenia dobândită în diverse stări patologice care afectează homeostazia osoasă. Diagnosticul precoce se stabileşte prin măsurarea densităţii osoase prin metode imagistice noninvazive, cele mai utilizate fiind dual-energy x-ray absorbtiometry (DEXA) şi ultrasonografia cantitativă. Tratamentul la copil se particularizează prin necesitatea adaptării aportului de calciu şi vitamina D atât la nevoile fiziologice ale creşterii, cât şi la cerinţele unei patologii. Tratamentul medicamentos specific cu bifosfonaţi ni trogenici a fost introdus la copii, dar nu este încă bine statuat. Atenţia care trebuie acordată acestei patologii osoase la copil şi adolescent este justificată de valoarea prognostică pentru tot restul vieţii a masei osoase de vârf a vârstei 20-21 ani.

Cuvinte cheie: osteopenie, copil, diagnostic, tratament

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Georgiana Russu

OSTEOPENIA IN CHILDHOOD AND ADOLESCENCE

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Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 4, An 2014
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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ICMJE- Recommendations

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Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

OSTEOPENIA IN CHILDHOOD AND ADOLESCENCE

Georgiana Russu, Tania Rusu, Ileana Ioniuc and Stela Gotia

ABSTRACT

Osteopenia, term of child pathologies, is a decrease in bone mass relative to chronological age, being an intermediate state between normal bone mass and osteoporosis. It has multiples etiological factors, comprising a heterogen group of diseases of the connective tissue with genetic determinism and osteopenia gained in various pathological conditions affecting bone homeostasis. Early diagnosis is determined by measuring bone density through non invasive imaging methods, the most common being dual-energy x-ray absorbtiometry (DEXA) and quantitative ultrasonography. Treatment in children customize through the need to adapt the intake of calcium and vitamin D to physiological growth needs and to requirements of some diseases. Specific drug treatment with nitrogen bisphosphonates was introduced to the children but is not yet well acted. Attention to be given to this bone pathologies in children and adolescents is warranted of its prognostic value for the rest of his life, to the peak bone mass of 20-21 years of age.

Keywords: osteopenia, children, diagnosis, treatment

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Georgiana Russu

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