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Dalia Dop

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Articole semnate de acelasi autor in Revista Romana de Pediatrie:

SINDROMUL STEVENS-JOHNSON (SSJ) SI NECROLIZA TOXICA EPIDERMALA DE ETIOLOGIE MEDICAMENTOASA

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Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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SINDROMUL STEVENS-JOHNSON (SSJ) SI NECROLIZA TOXICA EPIDERMALA DE ETIOLOGIE MEDICAMENTOASA

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REZUMAT

Sindromul Stevens-Johnson (SSJ) şi necroliza toxică epidermală (NTE) sunt afecţiuni rare care apar după administrarea medicamentelor cu risc. Ambele reprezintă grade de severitate ale aceleiaşi afecţiuni şi sunt considerate urgenţe medicale, deoarece sunt potenţial letale. Sunt caracterizate prin sensibilitate cutaneomucoasă, eritem, necroză şi dezlipire buloasă similar arsurilor extinse. În continuare vă prezentăm 3 cazuri de SSJ/NTE a căror etiologie a fost, probabil, medicamentoasă (Paracetamol, Atomoxetinum, Sulfamethoxazolum + trimethoprinum), cu refacere totală după administrarea de imunoglobuline intravenos.

Cuvinte cheie: sindromul Stevens-Johnson, necroliza toxică epidermală, etiologie medicamentoasă, imunoglobuline intravenos

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DRUG-INDUCED STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS

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Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

DRUG-INDUCED STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS

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ABSTRACT

Steven-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare diseases that appear following the administration of risk drugs. Both are severity grades of the same condition and are considered medical emergencies, because they are potentially lethal. They are characterized by mucocutaneous tenderness, erythema, necrosis and bullous detachment similar to extended burns. We report 3 cases of SJS/TEN in which the etiology was probably drug-related (Paracetamol, Atomoxetinum, Sulfamethoxazolum + trimethoprinum), with restitutio ad integrum following the administration of intravenous immunoglobulins.

Keywords: Steven-Johnson syndrome, toxic epidermal necrolysis, drug-related etiology, intravenous immunoglobulins

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EVALUAREA COPILULUI ALERGIC – UTILITATEA INVESTIGATIILOR PANEL

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Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

EVALUAREA COPILULUI ALERGIC – UTILITATEA INVESTIGATIILOR PANEL

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REZUMAT

Diagnosticul alergiilor pediatrice este în continuare o provocare complexă ţinând cot de incidenţa tot mai mare a acestei patologii. Obiectivele cercetării noastre au fost evaluarea utilităţii investigaţiilor panel în practica pediatrică. Am folosit copiii internaţi în Clinica de Pediatrie a Spitalului Municipal „Filantropia“ din Craiova. Evaluarea a fost făcută prin comparaţie cu un lot martor fără istoric de boli atopice. Sensibilizarea la alergeni respiratori (mai ales praf de casă) a fost cel mai frecvent întâlnită şi s-a coroborat în special cu patologia astmatică. Alergenii alimentari au fost mai rar identificaţi şi fără o corelaţie semnificativă cu modificările clinice.

Cuvinte cheie: copil, atopie, panel alergologic

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THE ASSESSMENT OF THE ATOPIC CHILDREN – PANEL TESTS

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Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

THE ASSESSMENT OF THE ATOPIC CHILDREN – PANEL TESTS

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ABSTRACT

The diagnosis in pediatric allergies is still a challenge, due to the age particularities and the increasing incidence.
Objectives. The evaluation of the panel investigations as a diagnostic tool in children allergies. We enrolled children admitted in the Department of Pediatrics of the “Filantropia” Clinical Municipal Hospital, Craiova. We used also a control group without known history of atopy.
Results. The results showed sensitizations to pneumallergens (mostly Dermatophagoides group) associated to asthma. The food allergies were identified in a few cases without correlation to the clinical findings.

Keywords: children, allergy, atopic panel

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