Articole semnate de acelasi autor in Revista Romana de Pediatrie:

SINDROMUL STEVENS-JOHNSON (SSJ) SI NECROLIZA TOXICA EPIDERMALA DE ETIOLOGIE MEDICAMENTOASA

Revista Romana de PEDIATRIE | Volumul LXV, Nr. 4, An 2016

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

Dalia Dop, Desdemona Stepan, Cristian Gheonea and Elena Carmen Niculescu

REZUMAT

Sindromul Stevens-Johnson (SSJ) şi necroliza toxică epidermală (NTE) sunt afecţiuni rare care apar după administrarea medicamentelor cu risc. Ambele reprezintă grade de severitate ale aceleiaşi afecţiuni şi sunt considerate urgenţe medicale, deoarece sunt potenţial letale. Sunt caracterizate prin sensibilitate cutaneomucoasă, eritem, necroză şi dezlipire buloasă similar arsurilor extinse. În continuare vă prezentăm 3 cazuri de SSJ/NTE a căror etiologie a fost, probabil, medicamentoasă (Paracetamol, Atomoxetinum, Sulfamethoxazolum + trimethoprinum), cu refacere totală după administrarea de imunoglobuline intravenos.

Cuvinte cheie: sindromul Stevens-Johnson, necroliza toxică epidermală, etiologie medicamentoasă, imunoglobuline intravenos

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Dalia Dop

DRUG-INDUCED STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Dalia Dop, Desdemona Stepan, Cristian Gheonea and Elena Carmen Niculescu

ABSTRACT

Steven-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare diseases that appear following the administration of risk drugs. Both are severity grades of the same condition and are considered medical emergencies, because they are potentially lethal. They are characterized by mucocutaneous tenderness, erythema, necrosis and bullous detachment similar to extended burns. We report 3 cases of SJS/TEN in which the etiology was probably drug-related (Paracetamol, Atomoxetinum, Sulfamethoxazolum + trimethoprinum), with restitutio ad integrum following the administration of intravenous immunoglobulins.

Keywords: Steven-Johnson syndrome, toxic epidermal necrolysis, drug-related etiology, intravenous immunoglobulins

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Dalia Dop