Lorena Elena Melit, Oana Cristina Marginean, Mihaela Chincesan, Andreea Dinca, Raluca Damian and Maria Oana Marginean

ABSTRACT

Burkitt lymphoma, a subtype of non-Hodgkin lymphomas, appears especially in small ages and it presents the most rapid tumor growth encountered in the human beings. We present the case of a 5 year-old child who presents diffuse, abdominal pain, abdominal distension and decreased consistency stools, and who is transferred in the Pediatrics Clinic 1 Targu-Mures, with the diagnosis of severe malnutrition and hypoproteinemia edema of unknown etiology. The laboratory investigations performed showed leukocytosis, mildly increased erythrocyte sedimentation rate, anemia, decreased level of serum proteins, and also an increased level of LDH. The abdominal ultrasound revealed intraperitoneal fluid, and the abdominal CT exam showed free fluid between the intestinal loops, 2 fistulas, one between the duodenum and the colon, and the other one between the jejunum and the colon, but also enlarged lymph nodes. The surprise during the surgery is the discovery of a tumor mass which involves the duodenum, the jejunum and the colon, and the pathological exam establishes the diagnosis of Burkitt lymphoma, extranodal type, with evolution after surgery burdened by multiple complications. After the third surgical intervention, the chemotherapy is initiated. Even though in some cases, the clinical picture is not suggestive for the severity of the pathology, the clinician’s perseverance is the one that finally leads to the establishment of the diagnosis.

Keywords: Burkitt lymphoma, child, diagnosis.

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Andreea Ligia Dinca, Oana Cristina Marginean, Lorena Elena Melit, Raluca Damian and Mihaela Chincesan

REZUMAT

Anemia aplastică este o patologie hematologică severă, potenţial fatală, caracterizată prin citopenie periferică şi măduvă osoasă hipocelulară, cu o prevalenţă de 2-6 cazuri la 1 milion locuitori. Prezentarea actuală ilustrează cazul unui copil de 9 ani, fără antecedente personale patologice cunoscute, şi cu debut brusc, aparent în plină stare de sănătate, diagnosticat cu anemie aplastică idiopatică severă şi cu evoluţie fulminantă. Lipsa de complianţă a părinţilor la actul medical, precum şi lipsa unei legislaţii care să protejeze copilul, au dus la decesul pa cientului într-un interval foarte scurt de timp.

Cuvinte cheie: copil, pancitopenie, anemie aplastică

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Andreea Ligia Dinca, Oana Cristina Marginean, Lorena Elena Melit, Raluca Damian and Mihaela Chincesan

ABSTRACT

Aplastic Anaemia is a severe potentially fatal haematological syndrome, characterised by peripheral pancytopenia and bone marrow hypoplasia, with an occurrence rate of 2-6 cases per million per year. This case report is about a 9 year-old boy, with no pathological known antecedents, and a sudden onset, apparently without any pathological associated conditions, who was diagnosed with severe Idiopathic Aplastic Anaemia, and a fulminate evolution. The lack of compliance of the parents regarding the therapy, and also the lack of a protective child’s legislation, led to patient’s death in a very short time.

Keywords: child, pancytopenia, aplastic anaemias

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