Articole semnate de acelasi autor in Revista Romana de Pediatrie:

COMPLICATII CARDIACE IN DISTROFIA MUSCULARA DUCHENNE LA COPIL

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 4, An 2015

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Ioana Grigore, Mariana Frasin and Georgeta Diaconu

REZUMAT

Complicaţiile cardiace sunt frecvent diagnosticate în distrofia musculară Duchenne (DMD), manifestările clinice fiind în general evidente după vârsta de 10 ani. Înregistrările electrocardiografice au obiectivat la aceşti pacienţi diferite modificări, cele mai frecvente fiind reprezentate de unde R ample în precordialele drepte, unde Q profunde stângi, tulburări de conducere şi aritmii. Examenul ecocardiografic poate obiectiva prezenţa disfuncţiilor cardiace subclinice la copiii cu vârstă sub 12 ani diagnosticaţi cu DMD. La pacienţii la care examenul ecocardiografic standard este în limite normale, indexul de performanţă miocardic este un parametru util în de pistarea precoce a anomaliilor cardiace asimptomatice. Rezonanţa magnetică cardiovasculară oferă informaţii atât cu privire la funcţia sistolică a ventriculului stâng, cât şi a modificărilor ţesutului miocardic şi a apariţiei fibrozei, leziuni ce rar pot fi obiectivate înaintea vârstei de 10 ani. Toate aceste explorări trebuie avute în vedere la copiii cu DMD la finalul unui bilanţ neurologic complet.

Cuvinte cheie: manifestări cardiace, distrofie musculară Duchenne, copil

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Ioana Grigore

CARDIAC COMPLICATIONS IN DUCHENNE MUSCULAR DYSTROPHY IN CHILDREN

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Ioana Grigore, Mariana Frasin and Georgeta Diaconu

ABSTRACT

Cardiac complications are frequently diagnosed in Duchenne muscular dystrophy (DMD), clinical manifestations generally appear after age 10. ECG recordings objectified various changes in these patients, the most common being represented by extensive R waves in V1, left deep Q waves, conduction abnormalities and arrhythmias. Echocardiographic examination may objective the presence of subclinical cardiac dysfunction in children under 12 years old diagnosed with DMD. In patients where standard echocardiographic examination is normal, myocardial performance index is a parameter useful in early detection of asymptomatic cardiac abnormalities. Cardiovascular magnetic resonance provides information both on left ventricular systolic function and myocardial tissue changes and occurrence of fibrosis, lesions rarely objectified before the age of 10 years. All these explorations should be considered in children with DMD at the end of a complete neurological exam.

Keywords: cardiac manifestations, Duchenne muscular dystrophy, child

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Ioana Grigore