Articole semnate de acelasi autor in Revista Romana de Pediatrie:

LIPOSARCOM OSOS PRIMAR LA COPIL

Revista Romana de PEDIATRIE | Volumul LXIII, Nr. 3, An 2014

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

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ICMJE- Recommendations

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Promoting Global Health

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Ingrid Miron, Gabriel Aprodu, Doina Mihaila, Petru Plamadeala, Oana Tatiana Miron, Anamaria Ciubara, Lucian Miron, Marin Burlea, Stefana Maria Moisa and Laurentiu Lucaci

REZUMAT

Introducere. Deşi liposarcomul de ţesuturi moi este o tumoră frecventă, liposarcomul primar osos este foarte rar, fi ind localizat în special în oasele lungi.

Material şi metodă. Prezentăm cazul unei paciente în vârstă de 14 ani, spitalizată în Spitalul Clinic de Urgenţă pentru Copii „Sfânta Maria“ din Iaşi pentru durere, impotenţă funcţională şi tumefacţia bratului drept, simptome ce au debutat cu 24 de ore anterior internării, ca urmare a unui traumatism prin cădere al braţului drept. Radiografi a osoasă a evidenţiat o masă tumorală în porţiunea proximală a humerusului, asociată cu o fractură patologică.

Rezultate. S-a realizat o biopsie la nivelul tumorii, iar analiza anatomopatologică (histologică şi imunochimică) a documentat proliferare liposarcomatoasă malignă.

Concluzie. Diagnosticul anatomopatologic fi nal, corelat cu examenul fi zic, care a exclus posibilitatea unei metastaze osoase liposarcomatoase, a fost aceea de liposarcom primar osos. Particularitatea cazului: tumoră foarte rară, cu prezentare iniţială de fractură osoasă patologică. În stabilirea diagnosticului de liposarcom osos primar, trebuie exclusă posibilitatea unei metastaze de la un liposarcom cu localizare iniţială extraosoasă, ca şi pe cea a unui alt tip de tumoră osoasă primară. Prognosticul pare a fi mai favorabil decât cel al osteosarcomului, dar liposarcomul prezintă o rată mai mare de recurenţe locale şi diseminări sistemice.

Cuvinte cheie: os, liposarcom, copil

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Ingrid Miron

PRIMARY BONE LIPOSARCOMA IN CHILDREN

ISSN 1454-0398 | e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

Ingrid Miron, Gabriel Aprodu, Doina Mihaila, Petru Plamadeala, Oana Tatiana Miron, Anamaria Ciubara, Lucian Miron, Marin Burlea, Stefana Maria Moisa and Laurentiu Lucaci

ABSTRACT

Introduction. Even though the soft tissue liposarcoma is a frequent tumor, the primary bone liposarcoma is very rare, being localized especially in the long bones.

Material and meyhod. We present the case of a 14 years old female child, hospitalized in the „Sf. Maria“ Emergency Clinic Hospital for Children Iasi accusing pain, functional impairment and tumefaction in the right arm, symptoms which suddenly occurred about 24 hours prior to presentation, following a falling trauma on the right arm. The bone x-ray emphasized a tumor in the proximal part of the humerus bone, associated with a pathological fracture.

Results. A biopsy form the tumor was performed and the pathology report (histology and immunohistochemistry) documented a malignant liposarcomatous proliferation.

Conclusion. The final pathology diagnosis, correlated with the clinical findings, which excluded the possibility of a bone metastasis, was that of a primary bone liposarcoma. Case particularity: very rare tumor, witch presented with a pathological bone fracture. In establishing the diagnosis of a bone liposarcoma it is very important to exclude a bone metastasis from a liposarcoma with a primary localization other than the bone, as well as other primary bone tumors. The prognosis seems to be better than in the osteosarcoma but liposarcoma presents a higher rate of local recurrence and systemic dissemination.

Keywords: bone, liposarcoma, child

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Ingrid Miron