National Awards “Science and Research”
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Solitary median maxillary central incisor syndrome – case report
Solitary median maxillary central incisor syndrome is a complex disorder consisting of multiple defects of development, mainly midline defects, secondary to the action of unknown factors operating in utero about the 35th-38th days from conception. The authors present a case of the child V.C. of 13 years and 9 months old, with repeated admissions for the assessment of short stature and mental retardation. At the age of 5 years the child was diagnosed with asthma, and at 10 years old with panhypopituitarism, and took inconstantly a thyroid replacement and growth hormone therapy. Clinical examination: severe short stature, facial dysmorphism, chronic nasal obstruction, the presence of a solitary median central incisor, moderate mental retardation with attention deficit. Laboratory examinations: cranial CT – pituitary hypoplasia; the hormonal tests confirmed the diagnosis of panhypopituitarism.
Key words: solitary median maxillary incisor syndrome, child