Romanian Journal of Pediatrics Logo
  • Home
  • Aims & Scope
  • Standards
    • Editorial policies
    • Instructions for authors
    • Peer review process
    • Guidelines for Reviewers
    • Ethics and Malpractice policies
    • Official Journal’s protocols & statements
    • Open Access
    • Fees
  • Editorial Council
  • Peer Review Council
  • EMC | CME
  • How to
  • SUBSCRIBE
  • Menu

Arhiva autor

  • About
  • Latest Posts

Carmen Zapucioiu

Latest posts by Carmen Zapucioiu (see all)

  • IMPORTANTA DIAGNOSTICULUI ETIOLOGIC IN INFECTIILE VIRALE SEVERE ALE TRACTULUI RESPIRATOR INFERIOR LA SUGAR SI COPIL - 17/07/2015
  • THE IMPORTANCE OF VIRAL ETIOLOGY DETERMINATION IN SEVERE LOWER RESPIRATORY TRACT INFECTIONS IN INFANTS AND CHILDREN - 17/07/2015
  • FENO SI ATOPIA IN ASTMUL BRONSIC LA COPII - 17/07/2015

Articole semnate de acelasi autor in Revista Romana de Pediatrie:

IMPORTANTA DIAGNOSTICULUI ETIOLOGIC IN INFECTIILE VIRALE SEVERE ALE TRACTULUI RESPIRATOR INFERIOR LA SUGAR SI COPIL

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 2, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

IMPORTANTA DIAGNOSTICULUI ETIOLOGIC IN INFECTIILE VIRALE SEVERE ALE TRACTULUI RESPIRATOR INFERIOR LA SUGAR SI COPIL

Alexandru-Ioan Ulmeanu, Carmen Zapucioiu, Maria Dorina Craciun and Coriolan Ulmeanu

REZUMAT

Introducere. Pneumonia comunitară reprezintă una din cauzele principale de deces în lume la copii cu vârsta sub 5 ani. Detecţia virală prin PCR multiplex este din ce în ce mai utilizată în practică, ea este utilă pentru a înţelege epidemiologia şi impactul virusurilor asupra populaţiei pediatrice însă există în continuare multe discuţii legate de cum influenţează detecţia virală modul efectiv de îngrijire al pacientului.

Obiective. În studiul efectuat ne-am propus analiza impactului pe care l-a avut identificarea etiologiei virale asupra duratei spitalizării şi asupra tratamentului administrat pe parcursul internării în spital.

Material şi metodă. Am efectuat un studiu retrospectiv pe o perioadă de 4 ani, au fost selectaţi copii între 0-5 ani cu infecţie severă de tract respirator inferior. Am comparat 3 grupuri: un grup cu infecţie virală specificată, un grup cu infecţie virală nespecificată şi un grup cu infecţie bacteriană.

Rezultate. În perioada analizată 72 de copii ce au prezentat semne de insuficienţă respiratorie acută au avut stabilit un diagnostic etiologic concret de infecţie virala, doar 2% din totalul infecţiilor virale diagnosticate în spital. Etiologia principală a fost reprezentată de virusul sinciţial respirator (VSR) în 73,5% dintre cazuri, urmat de Influenza cu 11%, Parainfluenza cu 4,2%, Metapneumovirusul (HMPV), Rinovirus, Bocavirus şi Adenovirus toate cu 2,8%. În cadrul infecţiei virale nespecifi cate s-au folosit antibiotice în 85,5% (n = 53) dintre cazuri. În cadrul infecţiei virale specificate deşi etiologia virală a fost certă, rata de folosire a antibioticelor a fost mai ridicată de 92% (n = 57) Durata spitalizării a fost în medie de cu 2,5 zile mai lungă în cadrul lotului cu infecţie virală specificată, faţă de lotul cu infecţie virală nespecifi cată. Deşi diagnosticul de infecţie virală a fost cert, dat fiind tabloul clinic sever şi vârsta mica a copiilor cheltuielile realizate pentru cei cu infecţie virală specificată au fost cu 30% mai mari faţă de cei cu infecţie virală nespecificată.

Concluzii. În studiul efectuat VSR este virusul cel mai frecvent implicat în etiologia ITRI virale, fiind implicat în forme severe de boală mai ales la sugarii mici şi foştii prematuri. Antibioterapia este utilizată în mod frecvent în formele severe de ITRI, chiar dacă etiologia virală este certă şi cunoscută, clasele de antibiotice folosite fiind asemănătoare. Determinarea etiologiei virale nu a redus spitalizarea, şi nici nu a dus la schimbarea atitudinii terapeutice a medicului curant.

Cuvinte cheie: pneumonie, bronşiolită, pneumonie virală, costuri spitalizare, antibioterapie

Full text | PDF

Alexandru-Ioan Ulmeanu

THE IMPORTANCE OF VIRAL ETIOLOGY DETERMINATION IN SEVERE LOWER RESPIRATORY TRACT INFECTIONS IN INFANTS AND CHILDREN

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 2, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

THE IMPORTANCE OF VIRAL ETIOLOGY DETERMINATION IN SEVERE LOWER RESPIRATORY TRACT INFECTIONS IN INFANTS AND CHILDREN

Alexandru-Ioan Ulmeanu, Carmen Zapucioiu, Maria Dorina Craciun and Coriolan Ulmeanu

ABSTRACT

Introduction. Community-acquired pneumonia is one of the leading causes of death worldwide in children under 5 years. In practice, viral detection using multiplex PCR is becoming increasingly used, it is most useful to understand the epidemiology and impact of viruses on the pediatric population but there are still many debates regarding the influence of viral detection on patient care.

Objectives. In this study we aimed to analyze the impact of viral etiology determination on the duration of hospitalization and on the administered treatment.

Material and methods. The selection criteria was: children between 0-5 years with severe lower respiratory tract infection. We have analyzed three groups of patients: a group with specified viral infection, a second group with unspecified viral infection and a third group with bacterial infection.

Results. In the analyzed period 72 children under 5 years of age who have shown signs of acute respiratory failure have been diagnosed with a specifi c viral infection, only 2% of the total viral infections. The main etiology was represented by respiratory syncytial virus (RSV) in 73.5% of cases, followed by Influenza 11%, Parainfluenza 4.2%, metapneumovirus (hMPV), Rhinovirus, Adenovirus and Bocavirus all with 2.8%. Within the unspecified viral infection group antibiotics were used in 85.5% (n = 53) of the cases. Within the specified viral infection group although viral etiology was firmly established antibiotics usage rate was higher 92% (n = 57). Duration of hospital stay was 2,5 days higher in the viral specified group compared with the unspecified one. Thus we found that although the diagnosis of viral infection was certainly given because of severe clinical picture and young age of children the expenses were 30% higher.

Conclusions. In our study, RSV is the most common virus involved in the etiology of viral LRTI and is encountered in the most severe forms of the disease especially in young infants and prematures. Antibiotics are commonly used in the severe forms of LRTI, even if the viral etiology is certain and the groups of antibiotics used are similar. Determination of viral etiology has not reduced hospitalization, nor has led to changing of physician therapeutic approach.

Keywords: pnemonia, bronchiolitis, viral pneumonia, hospital cost, antibiotics

Full text | PDF

Alexandru-Ioan Ulmeanu

FENO SI ATOPIA IN ASTMUL BRONSIC LA COPII

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 2, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

FENO SI ATOPIA IN ASTMUL BRONSIC LA COPII

Cristiana Stanciulescu, Mirela Chiru, Alina Oprea, Daniela Pacurar, Carmen Zapucioiu, Elena Petrisor and Dumitru Oraseanu

REZUMAT

Obiective. Stabilirea relaţiei între valoarea concentratiei oxidului nitric expirat (FENO) şi atopia în astmul bronşic la copii.

Metode. Au fost examinaţi 92 de pacienţi cu diagnosticul de astm bronşic stabilit, cu vârste cuprinse între 5 şi 18 ani, care s-au prezentat în Clinica de Pediatrie a Spitalului Clinic de Urgenţe pentru Copii „Grigore Alexandrescu“. Terenul atopic a fost evaluat prin date anamnestice, clinice şi investigaţii de laborator (eozinofile serice şi IgE totale). Tuturor pacienţilor li s-a determinat concentraţia oxidului nitric expirat.

Rezultate. S-au obţinut valori crescute ale FENO la copiii cu astm bronşic alergic faţă de cei cu astm bronşic nonalergic, valori care se corelează cu eozinofi lia şi creşterea imunoglobulinelor E totale.

Concluzii. Măsurarea FENO este utilă pentru evaluarea inflamaţiei mucoasei bronşice la copiii cu astm bronşic atopic.

Cuvinte cheie: FENO, eozinofilie, Ig E, astm, atopie

Full text | PDF

Cristiana Stanciulescu

FENO AND ATOPY IN PEDIATRIC ASTHMA

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 2, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

FENO AND ATOPY IN PEDIATRIC ASTHMA

Cristiana Stanciulescu, Mirela Chiru, Alina Oprea, Daniela Pacurar, Carmen Zapucioiu, Elena Petrisor and Dumitru Oraseanu

ABSTRACT

Objectives. The aim of this study was to determine the manner in which the level of exhaled nitric oxide (FENO) influences the atopic status in children with asthma.

Methods. The study included 92 asthmatic children (aged 5-18 years) admitted on the Pediatric Clinic of “Grigore Alexandrescu” Emergency Clinical Hospital for Children. The atopic status was evaluated through anamnesis, clinical examination and laboratory determination of serum eosinophils and total Ig E. All children underwent measurement of FENO.

Results. Children with atopic asthma had higher levels of FENO than children with nonatopic asthma. The FENO values correlate with eosinophilia and high values of immunoglobulin E.

Conclusion. FENO is a useful marker for the evaluation of airway infl ammation in children with atopic asthma.

Keywords: FENO, eosinophilia, IgE, asthma, atopy

Full text | PDF

Cristiana Stanciulescu

VIRUSURI RESPIRATORII NOI IN INFECTIILE DE TRACT RESPIRATOR INFERIOR LA COPIL: PROFILURI CLINICE SI EPIDEMIOLOGICE

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 1, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

VIRUSURI RESPIRATORII NOI IN INFECTIILE DE TRACT RESPIRATOR INFERIOR LA COPIL: PROFILURI CLINICE SI EPIDEMIOLOGICE

Alexandru-Ioan Ulmeanu, Carmen Zapucioiu and Coriolan-Emil Ulmeanu

REZUMAT

Infecţíile virale de tract respirator reprezintă una din cauzele principale de morbiditate şi mortalitate în patologia pediatrică. Autorii aduc informaţii de ultima oră privind structura, mecanismele patogenetice, caracteristicile clinice, epidemiologice şi răspunsul la tratament a unor virusuri descoperite recent care afectează tractul respirator la copil: bocavirusul, metapneumovirusul, coronavirusurile şi rhinovirusul C.

Cuvinte cheie: bocavirus, metapneumovirus, coronavirus, rhinovirus C, pneumonie, bronşiolită

Full text | PDF

Alexandru-Ioan Ulmeanu

CLINICAL AND EPIDEMIOLOGICAL PROFILES OF NOVEL VIRUSES IN LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXIV, Nr. 1, An 2015
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

CLINICAL AND EPIDEMIOLOGICAL PROFILES OF NOVEL VIRUSES IN LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN

Alexandru-Ioan Ulmeanu, Carmen Zapucioiu and Coriolan-Emil Ulmeanu

ABSTRACT

Viral respiratory tract infections are one of the leading causes of morbidity and mortality in pediatric pathology. The authors provide the latest information on the structure, pathogenesis, clinical features, epidemiology and response to treatment of newly discovered viruses affecting the respiratory tract in children: bocavirus, metapneumovirus, coronaviruses, rhinovirus C.

Keywords: bocavirus, metapneumovirus, coronaviruses, rhinovirus C, pneumonia, bronchiolitis

Full text | PDF

Alexandru-Ioan Ulmeanu


SEARCH

STANDARDE

  • Instructions for authors
  • Peer review process

Submit article

Submit your article to the journal by using the form here:

Submit

Subscriptions

To receive the Ro Journal of PEDIATRICS click here:

SUBSCRIBE
Publicare-RRPedia
Abonare_RRPedia

Partners

Partners logo

plic-maileditor@rjp.com.ro

Subscribe to the Newsletter

Articles from the journal are licensed under a 
Creative Commons Attribution 4.0 International License

 Terms & Conditions

Open Access Statement

Publisher : AMALTEA Medical Publishing House

The intended audience of the site content is professionals from the medical and pharmaceutical community.
This site does not collect any personal data nor does it use cookies that might obtain such data from your browser. [ info ]
Agree
Contact

Submit ARTICLE
E-mail: editor@rjp.com.ro  |  Mobile: +4 0742.155.512, M-F 09.00-18.00 EET

SUBSCRIPTIONS
E-mail: info@amaltea.ro |  Mobile: +4 0742.155.511, M-F 09.00-18.00 EET