Revista Romana de PEDIATRIE | Volumul LXI, Nr. 4, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398

Indexed in / abstracted by

Thomson Reuters Embase
Scopus Cross-ref
Index Copernicus
Ulrichs Ebsco Host
Medline - Ebsco PubMed


Publicarea de articole stiintifice

Stimati cititori, va reamintim ca autorii primi ai articolelor stiintifice pot acumula 80 de credite EMC in urma publicarii. Daca un articol are mai multi autori, cele 80 de credite [...]

Premiul Societatii pentru autori

Incepand cu 2016, Societatea Romana de Pediatrie ofera Premiul Societatii - pentru autorii celor mai bune articole stiintifice publicate [...]

Plagiatul – in actualitate

Tema plagiatului este tot mai mult discutata in ultima vreme. Aparitia unor programe performante de cautare si identificare a similitudinilor intre texte [...]

The infection – risk factor for asthma in children



According to hygiene theory, the infectious agents gives some protection against asthma by initiating a Th1 type immune defense mechanism. Now this issue is reconsidered, demonstrating that certain viral or bacterial infection occurring mainly in children at risk of personal and / or family atopy can trigger asthma by deviating the immune response towards TH2 line. In the initiation and maintenance of this “switch-up” mechanism are involved a number of factors in relation to bronchial epithelial cell whose action is modulated by genes. The knowledge of these mechanisms opens new therapeutic perspectives in the treatment of asthma in children.

Key words: bronchial asthma, infections, child

Full text | PDF

Leave a Reply