Revista Romana de PEDIATRIE | Volumul LX, Nr. 4, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexată BDI  |  IDB Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
Ebsco Host - Medline
Google Academic
Semantic Scholar


Publicarea de articole științifice

Stimați cititori, vă reamintim că autorii primi ai articolelor științifice pot acumula 80 de credite EMC în urma publicării. Dacă un articol are mai mulți autori, cele 80 de credite [...]


RJP și SRPed oferă anual Premiul Național pentru Știință și Cercetare - pentru autorii celor mai bune articole științifice publicate [...]

Plagiatul – în actualitate

Tema plagiatului este tot mai mult discutată în ultima vreme. Apariția unor programe performante de căutare și identificare a similitudinilor între texte [...]



New benchmarks in the study of biological effects of vitamin D


Recent dosage of vitamin D for clinical usage had changed completely the understanding of pathology including its deficit. It was seen that insufficient/deficit of vitamin D are encountered in the population of developed countries and surprisingly in population that live in warm climate. Only a level of the blood levels of vitamin D may be linked to seasonality, latitude or oral intake. The genetic factors may manifest in all its metabolism process. The genes that infl uence the vitamin D level are DHCR7, CYP27A1, CYP2R1 and VDR, CYP24A1 and Gc gene. There are presented the steps of vitamin D metabolism as well as the intervention of different genes in the individual network. Through its autocrine function vitamin D facilitates the expression of genes in cell function its action being pleitropic. There are also listed some of the other disorders apart of rickets that are inluenced by the low level of vitamin D.

Key words: vitamin D, genes, low level, rickets, chronic disease

Full text | PDF

Leave a Reply