Revista Romana de PEDIATRIE | Volumul LXII, Nr. 3, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398

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Anaphylaxis in child


Anaphylaxis is a severe allergic reaction with possible fatal evolution, determined by mast cells and basophiles mediators abruptly discharged, by IgE (most frequently) or nonIgE mechanisms. Risk factors for anaphylaxis and those which increase the risk of fatal anaphylaxis modulate the rapidity of the onset (10-20 minutes) and the severity of the clinical response (from common symptoms to shock). The practical guidelines for diagnosis and treatment of anaphylaxis updated in 2012 established the diagnosis criteria, the treatment steps in this major emergency and the follow-up. To know and to apply this guideline in all the medical utilities became a major target for the continuous medical education in all the countries.

Key words: anaphylaxis, child, anaphylactic shock, guideline

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