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Revista Romana de PEDIATRIE | Volumul LX, Nr. 4, An 2011
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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The frequency of urinary tract infections in children with antenatal hydronephrosis

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ABSTRACT

Infants with antenatal hydronephrosis are at risk 12 times greater of developing acute pyelonephritis. We evaluated the frequency of urinary tract infections (UTI) in a group of 87 patients with congenital hydronephrosis (HN) detected antenatally (ratio B: F = 2,95:1). The average follow-up was 20.22 months. 49.42% of children had UTI, the recurrence rate (≥ 2 episodes) was 53.8%. Depending on the degree of hydronephrosis, urinary infection rate was between 37.5 to 41.37% for grade I-II HN and between 57-71% for grade III-V HN (p = 0.0402, 95% CI grade I-II HN compared with grade III-V). We found a weak positive correlation between the degree HN and the number of UTI (rs = 0.224, p = 0.036, 95% CI) significant statistic. 60.52% of patients with a history of UTI had urinary infections on uroprophylaxis. Cefaclor was the most common used antibiotic. E coli was involved in 36.35% of UTI, and Klebsiella pn. 25%. Given the high frequency of urinary infections in this group, it is neccesary a longer follow-up of these children for early detection of kidney damage.

Key words: congenital hydronephrosis, urinary tract infections, uroprophylaxis, antenatal diagnosis, UTI reccurence, antenatal hydronephrosis

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