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A.G. Dimitriu

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Articole semnate de acelasi autor in Revista Romana de Pediatrie:

Pulmonary atresia – unfavorable prognostic factor in tetralogy of Fallot with neonatal onset

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Revista Romana de PEDIATRIE | Volumul LXI, Nr. 1, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Pulmonary atresia – unfavorable prognostic factor in tetralogy of Fallot with neonatal onset

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ABSTRACT

Infundibular or valvular pulmonary atresia occurs in 15-25% of tetralogy of Fallot cases, is manifested clinically in the neonatal period, is included in the ductdepedent congenital heart disease (CHD), requires prostaglandin E1 infusion and early surgical treatement. Tetralogy of Fallot may associate more anatomical variants, some with poor prognosis in the first year of life, if the cardiovascular surgery is not performed in time, most commonly in the neonatal period. The aim of this article is presenting a clinical case of tetralogy of Fallot and pulmonary atresia, diagnosed in the neonatal period, with severe cyanosis and had a progression to death whithin 6 months of life. Pathologic examination revealed malformative association: renal left hypoplasia, with left megaureter and hidrocalicosis without urinary tract infection.

Key words: infant, cyanosis, tetralogy of Fallot, pulmonary artery atresia, pathological examination

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ATREZIA PULMONARA – FACTOR DE PROGNOSTIC NEFAVORABIL IN TETRALOGIA FALLOT CU DEBUT NEONATAL

SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXI, Nr. 1, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

Indexed

DOI - Crossref
Similarity Check by iThenticate, worldwide No 1 professional plagiarism checking system
DOAJ
Scopus
NLM Catalog
Ebsco Host - Medline
Google Academic
Semantic Scholar

HIGHLIGHTS

National Awards “Science and Research”

NEW! RJP has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

ATREZIA PULMONARA – FACTOR DE PROGNOSTIC NEFAVORABIL IN TETRALOGIA FALLOT CU DEBUT NEONATAL

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REZUMAT

Atrezia infundibulară sau valvulară pulmonară apare la 15-25% dintre cazurile de tetralogie Fallot, se manifestă clinic din perioada neonatală, fiind inclusă în cardiopatiile congenitale critice ductodependente, impunând perfuzie endovenoasă cu prostaglandine E1 şi tratament chirurgical precoce. Tetralogia Fallot poate asocia mai multe variante anatomice, unele cu prognostic nefavorabil în primul an de viaţă, în cazul în care intervenţia chirurgicală cardiovasculară nu este efectuată în timp util, cel mai frecvent în perioada neonatală. Este prezentat un caz clinic de tetralogie Fallot şi atrezie de valvă pulmonară (VP), diagnosticat în perioada neonatală, când a prezentat cianoză severă şi care a avut o evoluţie spre deces în primele 6 luni de viaţă. Examenul anatomopatologic a evidenţiat asocieri malformative: hipoplazie renală stângă, cu megaureter şi hidrocalicoză stângă, fără infecţie de tract urinar.

Cuvinte cheie: sugar, cianoză, tetralogie Fallot, atrezie de arteră pulmonară, examen anatomopatologic.

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