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Revista Romana de PEDIATRIE | Volumul LXII, Nr. 4, An 2013
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398

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Publicarea de articole stiintifice

Stimati cititori, va reamintim ca autorii primi ai articolelor stiintifice pot acumula 80 de credite EMC in urma publicarii. Daca un articol are mai multi autori, cele 80 de credite [...]

Premiul Societatii pentru autori

Incepand cu 2016, Societatea Romana de Pediatrie ofera Premiul Societatii - pentru autorii celor mai bune articole stiintifice publicate [...]

Plagiatul – in actualitate

Tema plagiatului este tot mai mult discutata in ultima vreme. Aparitia unor programe performante de cautare si identificare a similitudinilor intre texte [...]

MARSHALL SYNDROME (PFAPA). EXPERIENCE OF PEDIATRIC CLINIC FROM SIBIU

and

ABSTRACT

PFAPA is a chronic condition including recurrent fever episodes, aphthous stomatitis, pharyngitis and adenitis. The authors emphasize peculiarities regarding diagnosis, evolution and citokinic profile for PFAPA patients. 22 patients with PFAPA were included in study. Patients that fulfilled diagnosis criteria were analyzed regarding symptoms onset age, period of time between episodes and between disease onset and diagnosis and also data about inflammatory status. Authors compared 2 groups: “PFAPA group” including 6 patients (between febrile episodes) and “Non-PFAPA group” including 4 healty children. Both gropus were analyzed regarding serum levels of inflammatory markers and cytokines in order to identify a biological sensitive marker for PFAPA evolution pattern. Data was statistically analyzed using “independent sample t test”. Results. Authors noticed a low suspicion index for PFAPA diagnosis (underdiagnosed disorder) and significant statistical differences between the 2 groups regarding C reactive protein (CRP) serum value. Conclusions. PFAPA diagnosis is established lately, so it’s useful to disseminate information about disease. CRP remains a sensitive marker for disease activity in PFAPA patients, even out of fever attacks.

Key words: Marshall syndrome, child

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