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Revista Romana de PEDIATRIE | Volumul LXI, Nr. 4, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398
DOI: 10.37897/RJP

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Toxic nephropathies in children

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ABSTRACT

Toxic nephropathies in children are rare entities but important to diagnoze early due to severe evolution and the need for rapid treatment. In the face of toxic acute renal failure the primary objective is to specify whether the ARF is organic or functional. Although serum creatinine remains the main laboratory test for diagnosis and monitoring toxic acute renal failure, new markers can be used for rapid and early detection of renal injury. In this paper the authors present the renal involvement in acute poisoning in children, classifi cation and etiopathogenesis of toxic nephropathies, and practical approach in assessing nephrotoxicity.

Key words: toxic nephropathy, acute renal failure, nephrotoxicity

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