SELECT ISSUE

Revista Romana de PEDIATRIE | Volumul LXI, Nr. 2, An 2012
ISSN 1454-0398  |  e-ISSN 2069-6175
ISSN-L 1454-0398

Indexed in / abstracted by

Thomson Reuters Embase
Scopus Cross-ref
Index Copernicus
Ulrichs Ebsco Host
Medline - Ebsco PubMed

HIGHLIGHTS

Publicarea de articole stiintifice

Stimati cititori, va reamintim ca autorii primi ai articolelor stiintifice pot acumula 80 de credite EMC in urma publicarii. Daca un articol are mai multi autori, cele 80 de credite [...]

Premiul Societatii pentru autori

Incepand cu 2016, Societatea Romana de Pediatrie ofera Premiul Societatii - pentru autorii celor mai bune articole stiintifice publicate [...]

Plagiatul – in actualitate

Tema plagiatului este tot mai mult discutata in ultima vreme. Aparitia unor programe performante de cautare si identificare a similitudinilor intre texte [...]

Inhaled steroids for children: effects on growth

, and

ABSTRACT

The effect of long-term use of inhaled corticosteroid (ICS) on growth in asthmatic children and adolescents remain a controversial issue.

Objective: To determine whether inhaled steroid therapy causes delayed linear growth and other anthropometric parameters change (height, weight, body mass index – BMI) in children with asthma in a 2 years survey.

Methods: 76 children (5-18 years old) with mild to severe persistent asthma treated with inhaled coricosteroids alone or in association with long acting beta agonist therapy and other anti-inflammatory therapy (montelukast) in conformity with GINA 2006 guideline was assessed in Department of Clinical Allergology and Immunology “St. Marie” Children Hospital – Iassy. The dynamic relationship between ICS – dose and linear growth was followed. Height/age, weight/age and BMI/age Z scores were calculated every twelve months and the data obtained was compared with those recorded from 75 children – control group.

Results: after 2 years of ICS use in children with asthma we found a decrease in height gain velocity especially in the second year of survey (p=0,012), without any statistical significant impact on weight and BMI. There was no correlation between the level of ICS dose (small, medium or height) and the growth curve in height, weight and BMI.

Conclusions: long-term ICS therapy might affect the linear growth in children with asthma regardless of dose, without a significant impact on weight or BMI.

Key words: asthma, inhaled corticosteroid therapy, velocity of linear growth

Full text | PDF

Leave a Reply